In the intricate landscape of chemical manufacturing, certain molecules serve as linchpins for a vast array of downstream products. 5-Fluoro-2-methylbenzonitrile, identified by its CAS number 77532-79-7, is one such critical intermediate. Its unique chemical structure and reactivity make it indispensable in sectors ranging from pharmaceuticals to advanced materials. This article provides an overview of its chemical properties and discusses the commercial aspects of its procurement, focusing on its availability from leading manufacturers and suppliers.

Chemical Profile: A Versatile Intermediate

5-Fluoro-2-methylbenzonitrile is an organic compound characterized by its benzonitrile core bearing a fluorine atom and a methyl group. Its molecular formula, C8H6FN, and a molecular weight of approximately 135.14 g/mol, detail its composition. The presence of the electron-withdrawing fluorine atom and the reactive nitrile group (-C≡N) confers distinct chemical properties. The nitrile group can be readily transformed through reduction, hydrolysis, or nucleophilic addition reactions, paving the way for the synthesis of diverse compounds like amines, amides, and carboxylic acids. The fluorine substituent often imparts enhanced metabolic stability and lipophilicity, qualities highly valued in medicinal chemistry. Typically appearing as an off-white crystalline powder, its high purity (often ≥99.0%) is essential for demanding synthetic applications.

Key Applications and Market Demand

The primary driver for the demand of 5-Fluoro-2-methylbenzonitrile is its role as a pharmaceutical intermediate. It is extensively used in the synthesis of Active Pharmaceutical Ingredients (APIs), where the precise introduction of fluorinated aromatic moieties can significantly improve drug efficacy and pharmacokinetic profiles. Beyond pharmaceuticals, this compound finds utility in the agrochemical industry and in the development of specialty chemicals and materials requiring specific structural attributes. The consistent need for this intermediate underscores the importance of a robust global supply chain.

Procurement: Finding a Reliable Supplier and Competitive Price

For businesses looking to buy 5-Fluoro-2-methylbenzonitrile, partnering with a reliable manufacturer and supplier is crucial. NINGBO INNO PHARMCHEM CO.,LTD., a prominent chemical manufacturer based in China, offers this intermediate with a commitment to high quality and competitive pricing. When sourcing, buyers should prioritize suppliers who can provide:

  • Guaranteed High Purity: Certificates of Analysis (COA) verifying purity levels are essential.
  • Competitive Pricing: Especially for bulk purchases, securing cost-effective options is vital for project viability.
  • Supply Chain Stability: Reliable production capacity and timely delivery ensure that R&D and manufacturing timelines are met.
  • Comprehensive Documentation: Access to MSDS and other relevant safety and technical information is standard practice.

Understanding the market dynamics and engaging with experienced suppliers can ensure a seamless procurement process for this essential chemical building block. Whether for research purposes or large-scale production, ensuring a consistent and high-quality supply of 5-Fluoro-2-methylbenzonitrile CAS 77532-79-7 is key to driving innovation and success in the chemical industry.