In the dynamic field of pharmaceutical research and development, identifying and sourcing high-quality chemical intermediates is paramount. Among these, 5-Iodouracil (CAS 696-07-1) stands out as a critical pyrimidine derivative with significant applications. As a trusted manufacturer and supplier of fine chemicals, understanding the utility of compounds like 5-Iodouracil is central to supporting innovation.

What is 5-Iodouracil?

5-Iodouracil is a halogenated pyrimidine, essentially a uracil molecule with an iodine atom attached at the 5-position. This structural modification imbues it with unique properties that are highly valuable in various biochemical and pharmaceutical contexts. Its chemical formula is C4H3IN2O2, and it typically presents as a white powder. As a reliable chemical supplier in China, we ensure that the 5-Iodouracil we provide meets stringent purity standards, often exceeding 97% purity as determined by HPLC.

Key Applications in Pharmaceutical Synthesis and Research

The significance of 5-Iodouracil lies in its diverse applications:

  • Nucleoprotein Photo-crosslinking: One of its primary uses is in nucleoprotein photo-crosslinking via RNA substitution. This process is vital for understanding molecular interactions within cells and is a key technique in molecular biology research.
  • Targeted Imaging and Therapy: 5-Iodouracil plays a role in thymidine phosphorylase targeted imaging and therapy. This application is particularly relevant in the development of advanced cancer treatments where specificity is crucial.
  • Biochemical Studies: Research indicates that enzymes like DNA N-glycosylase MED1 show a higher preference for 5-Iodouracil and other halogenated bases compared to non-halogenated ones. This makes it an important tool for studying enzyme-nucleic acid interactions.
  • Antiviral and Anticancer Agent Development: Due to its antimetabolite properties, 5-Iodouracil is a valuable building block in the synthesis of potential antiviral and anticancer drugs. Pharmaceutical companies looking to buy 5-Iodouracil for drug discovery often seek high-purity grades for their formulation work.

Sourcing High-Quality 5-Iodouracil

For B2B procurement managers and R&D scientists, securing a consistent and reliable source for chemical intermediates is critical. When you need to buy 5-Iodouracil, partnering with a reputable manufacturer is essential. We pride ourselves on being that partner, offering not just the product but also the assurance of quality and timely delivery. Our commitment as a leading pharmaceutical intermediate supplier means we understand the rigorous demands of the industry.

The ability to obtain 5-Iodouracil at a competitive price, coupled with strong technical support and clear documentation, is what sets leading chemical suppliers apart. Whether for early-stage research or scaled-up production, ensuring the purity and availability of 5-Iodouracil directly impacts project success. We invite you to explore our offerings and experience the reliability that comes from working with a dedicated chemical manufacturer.