In the realm of advanced chemical research, specialized compounds serve as the bedrock for groundbreaking discoveries. 5-Iodouracil (CAS 696-07-1) is one such molecule, a potent pyrimidine derivative recognized for its versatile applications across scientific disciplines. For R&D scientists and procurement specialists seeking to buy 5-Iodouracil, understanding its unique properties and securing a dependable supply chain is crucial.

Understanding 5-Iodouracil's Chemical Identity

5-Iodouracil is a derivative of uracil, a fundamental component of nucleic acids. The presence of an iodine atom at the 5-position significantly alters its chemical behavior and biological interactions. Its molecular formula, C4H3IN2O2, points to a relatively simple yet powerful structure. Typically appearing as a white to off-white powder, its purity is a critical factor for its effective use. As a global chemical supplier, we prioritize delivering 5-Iodouracil with high purity, often exceeding 97% (HPLC), to meet the exacting demands of research laboratories.

Key Research Applications Driving Demand

The utility of 5-Iodouracil extends across several critical areas of scientific inquiry:

  • Biochemical Mechanism Studies: Scientific studies have shown that 5-Iodouracil is recognized by enzymes such as DNA N-glycosylase MED1, exhibiting a higher preference for it and other halogenated bases. This makes it an invaluable tool for researchers investigating enzymatic pathways and base-pairing mechanisms in molecular biology.
  • Drug Discovery and Development: As a building block and pharmaceutical intermediate, 5-Iodouracil is instrumental in the synthesis of potential therapeutic agents. Its antimetabolite properties are explored in the design of novel antiviral and anticancer drugs. Researchers often look to purchase 5-Iodouracil for its role in modifying DNA and RNA structures.
  • RNA Research and Cross-linking: Its application in nucleoprotein photo-crosslinking via RNA substitution allows scientists to map and understand complex cellular machinery. This technique is vital for proteomic and genomic studies.
  • Targeted Therapies: The compound's involvement in thymidine phosphorylase targeted imaging and therapy underscores its importance in the development of sophisticated medical treatments, particularly in oncology.

Partnering with a Reliable Chemical Manufacturer

For institutions and companies involved in cutting-edge research, the choice of a chemical manufacturer or supplier can significantly impact project timelines and outcomes. When seeking 5-Iodouracil, prioritizing quality, consistency, and competitive pricing is essential. We aim to be your trusted partner, providing a stable supply of high-purity 5-Iodouracil, backed by responsive customer service and comprehensive product information. As a dedicated fine chemical supplier, we ensure that your procurement process is seamless and efficient, allowing you to focus on your research objectives.