In the complex landscape of pharmaceutical manufacturing, the quality and reliability of raw materials are paramount. Among the many essential chemical compounds, 8-[(2-hydroxybenzoyl)amino]octanoic acid stands out for its pivotal role in enhancing drug delivery systems. As a dedicated manufacturer and supplier, we offer this high-purity pharmaceutical intermediate, crucial for developing next-generation therapeutics.

Also known by its common name, salcaprozic acid, and often used in its sodium salt form (SNAC), this compound is scientifically valued for its ability to promote oral absorption of macromolecules. This capability addresses a major challenge in pharmaceutical development: ensuring that potent drugs can be effectively delivered to the bloodstream through oral administration.

Understanding the Chemistry of 8-[(2-hydroxybenzoyl)amino]octanoic Acid

Chemically, 8-[(2-hydroxybenzoyl)amino]octanoic acid (CAS No. 183990-46-7) is an organic compound with the molecular formula C₁₅H₂₁NO₄. Its structure features an octanoic acid backbone linked via an amide bond to a 2-hydroxybenzoyl group. This amphiphilic nature is key to its function as an absorption enhancer. The salicylic acid-derived moiety contributes to its pH-modulating properties, while the aliphatic chain aids in interacting with biological membranes.

The synthesis of this compound involves sophisticated chemical processes to ensure high purity, which is critical for its application in pharmaceutical formulations. Established synthetic routes often involve amide bond formation between suitable derivatives of salicylic acid and 8-aminooctanoic acid. As a manufacturer, we employ optimized methodologies to guarantee yields and purity, typically exceeding 99%, making our product ideal for pharmaceutical use.

Why is it a Crucial Pharmaceutical Intermediate?

The primary application of 8-[(2-hydroxybenzoyl)amino]octanoic acid lies in its function as a permeation enhancer. For drug developers, this means:

  • Improved Oral Bioavailability: It enables drugs that are poorly absorbed orally to reach therapeutic levels in the body, potentially replacing injections with convenient oral dosage forms.
  • Enhanced Delivery of Biologics: It is particularly effective for peptide and protein-based drugs, which are inherently challenging to deliver orally.
  • Support for Innovative Formulations: Its versatility allows it to be incorporated into various delivery systems, including tablets, capsules, and liquids, enhancing patient compliance.

For companies seeking to buy this essential intermediate, choosing a reliable supplier is paramount. Our commitment as a manufacturer ensures a consistent supply of high-quality 8-[(2-hydroxybenzoyl)amino]octanoic acid, meeting the stringent demands of pharmaceutical R&D and manufacturing.

Partnering with a Trusted Supplier

When you choose us as your supplier, you are partnering with an experienced manufacturer dedicated to quality and innovation. We understand that the efficacy of your final drug product depends on the purity and consistency of the raw materials. We offer competitive pricing for bulk purchases and are ready to support your project from early-stage research to full-scale production.

If your research and development efforts require a dependable source of 8-[(2-hydroxybenzoyl)amino]octanoic acid, we invite you to contact us. Discover how our commitment to excellence can benefit your pharmaceutical formulation and help bring more effective oral therapies to market. Inquire about our supply chain and secure your critical intermediate today.