In the intricate world of organic synthesis, certain molecules stand out for their versatility and indispensable role in constructing complex architectures. 6-Hydroxy-1-indanone (CAS: 62803-47-8) is one such compound, a valuable building block that enables chemists to forge novel materials and potent pharmaceutical agents. For R&D scientists and procurement specialists, understanding its synthetic potential and identifying reliable sources is key to successful innovation. This article explores why this compound is a go-to reagent for advanced organic synthesis, and where to find it when you need to buy.

The core structure of 6-Hydroxy-1-indanone, featuring a hydroxyl group and a ketone on an indanone backbone, provides multiple reactive sites, making it a highly adaptable intermediate. Its utility spans from the creation of intricate natural product analogues to the development of cutting-edge materials.

One of the most significant applications of 6-Hydroxy-1-indanone is in the synthesis of complex organic molecules, including various natural products. Researchers have utilized it as a starting material in the total synthesis of compounds like (±)-frondosin C. This involves intricate multi-step processes where the indanone framework is elaborated to form fused ring systems, demonstrating the molecule's capacity to contribute to the construction of highly functionalized and biologically relevant scaffolds. When you require this crucial building block for your natural product synthesis projects, finding a dependable manufacturer who can supply high-purity material is essential.

Beyond natural product synthesis, 6-Hydroxy-1-indanone plays a pivotal role in the creation of specialized chemical entities. It is a precursor to 1,4-dihydroindeno[1,2-c]pyrazoles, which are potent inhibitors of Checkpoint Kinase 1 (CHK-1). The development of such inhibitors is a vital area in cancer research, aiming to disrupt cancer cell proliferation. This application alone underscores the importance of having access to this compound for specialized pharmaceutical intermediate synthesis.

For those looking to integrate 6-Hydroxy-1-indanone into their synthetic workflows, understanding its properties is beneficial. Typically available as a yellow powder with a purity of 97%, it is soluble in methanol, facilitating its use in a variety of reaction conditions. When sourcing this chemical, consider partnering with established suppliers in China who can guarantee consistent quality and competitive prices. Requesting a quote and inquiring about bulk packages can help optimize procurement for research and production.

The journey from basic chemical intermediate to advanced therapeutic or material is paved with molecules like 6-Hydroxy-1-indanone. Its ability to undergo diverse chemical transformations makes it an invaluable asset in the organic chemist's toolkit. Whether you are engaged in academic research or industrial product development, ensuring a steady supply of this vital intermediate from a trusted partner is paramount.