In the relentless pursuit of novel cancer therapies, the identification and synthesis of key intermediate compounds are paramount. One such vital molecule gaining significant attention is 6-Hydroxy-1-indanone (CAS: 62803-47-8). This versatile chemical serves as a cornerstone for developing advanced pharmaceutical agents, particularly those targeting cancer cell growth. For procurement managers and R&D scientists seeking reliable sources, understanding its applications and finding trustworthy manufacturers is crucial.

The significance of 6-Hydroxy-1-indanone lies in its structural capacity to act as a precursor for two critical classes of compounds. Firstly, it is instrumental in the total synthesis of complex tetracyclic ketone intermediates, such as those required for natural products like (±)-frondosin C. These complex molecular architectures are often the foundation for novel drug discovery.

Secondly, and perhaps more impactfully in the immediate fight against cancer, 6-Hydroxy-1-indanone is a key intermediate in the synthesis of 1,4-dihydroindeno[1,2-c]pyrazoles. These compounds are recognized for their potent ability to inhibit Checkpoint Kinase 1 (CHK-1). CHK-1 is a crucial enzyme involved in DNA damage response, and its inhibition can lead to cell cycle arrest and apoptosis in cancer cells, making it a prime target in oncology. Researchers looking to buy these CHK-1 inhibitor precursors can rely on high-purity grades of 6-Hydroxy-1-indanone.

For industries requiring a consistent and high-quality supply, sourcing 6-Hydroxy-1-indanone from reputable suppliers in China is a strategic advantage. Companies offering this compound often emphasize its purity (typically 97%) and availability in various packaging sizes, catering to both laboratory-scale research and larger production demands. When inquiring about the price, it is advisable to look for manufacturers who can provide detailed specifications, certificates of analysis, and potentially free samples to ensure suitability for your specific application.

The compound's physical properties, such as its yellow powder appearance and solubility in methanol, further enhance its utility in various synthetic protocols. As the demand for innovative cancer treatments continues to grow, intermediates like 6-Hydroxy-1-indanone will remain indispensable. Ensuring a stable supply chain and partnering with reliable chemical manufacturers is key to advancing pharmaceutical research and bringing life-saving therapies to market.