The pharmaceutical industry operates under a microscope, where every component, especially those used in the synthesis of Active Pharmaceutical Ingredients (APIs), must meet exacting standards. For Diclofenac, a globally recognized non-steroidal anti-inflammatory drug (NSAID), the purity of its precursors directly dictates the quality and safety of the final product. 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide (CAS 15308-01-7) is one such indispensable intermediate. Its precise chemical structure and reactivity are fundamental to the successful and pure synthesis of Diclofenac. This article highlights the importance of this intermediate and the critical role it plays in achieving API purity.

As a manufacturer of pharmaceutical intermediates, our focus is on providing materials that not only meet but exceed the stringent quality expectations of our clients. 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide, with its defined chemical properties – a white to off-white crystalline powder, a molecular weight of 314.59, and a formula of C14H10Cl3NO – is produced under rigorous quality control measures. The chemical synthesis of Diclofenac from this precursor requires precise reaction conditions and highly pure starting materials. Any deviation in the quality of 15308-01-7 can introduce unwanted impurities into the subsequent stages of API production, potentially leading to:

  • Reduced yield of Diclofenac.
  • Presence of by-products that require extensive purification.
  • Potential for genotoxic or otherwise harmful impurities in the final API.
  • Non-compliance with regulatory pharmacopeial standards (USP, EP, etc.).

Therefore, when R&D scientists or procurement managers are looking to purchase this intermediate, the specifications provided by the supplier are of utmost importance. A high assay value (NLT 99.0%) and low levels of related substances are critical indicators of a quality product. Furthermore, understanding the packaging and storage conditions recommended by the manufacturer (e.g., stored in a cool, dry, ventilated place) helps maintain the integrity of the compound until it is used in the synthesis. Choosing a reliable supplier in China that provides comprehensive analytical data, including HPLC chromatograms and impurity profiling, is a proactive step towards ensuring API purity.

The chemical industry, particularly the pharmaceutical sector, places immense value on consistency and traceability. By specifying and sourcing 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide with clear and verifiable quality parameters, companies can build a robust and reliable manufacturing process for Diclofenac. Our commitment as a supplier is to provide precisely this level of assurance, ensuring that the intermediates we supply contribute positively to the purity and efficacy of the final pharmaceutical product. We encourage you to enquire about our product specifications and pricing for your Diclofenac production needs.

In essence, the quality of a pharmaceutical intermediate like 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide is not merely a technical detail; it is a foundational element for producing safe and effective medicines. Partnering with a diligent manufacturer and supplier is key to navigating the complexities of API synthesis and upholding the highest standards of pharmaceutical quality.