The journey from a novel compound to a market-ready drug is complex, and at its heart lies the availability of high-quality chemical intermediates. 4-Bromo-2,5-difluorobenzoic Acid (CAS: 28314-82-1) has emerged as a vital building block, enabling significant advancements in pharmaceutical research. This article delves into its primary applications and guides you on how to procure this essential material from trusted manufacturers.

Enabling Novel Therapeutic Development

The versatility of 4-Bromo-2,5-difluorobenzoic Acid stems from its reactive functional groups and the influence of its halogen substituents, making it a prime candidate for synthesizing complex molecular architectures. One of its most prominent roles is as an intermediate in the preparation of GPR119 agonists. These compounds are being investigated for their therapeutic potential in managing conditions like type 2 diabetes and obesity by targeting the G protein-coupled receptor 119. Researchers looking to buy this intermediate for such projects require consistent purity and reliable supply.

Another significant application lies in the field of epigenetics and cancer research. 4-Bromo-2,5-difluorobenzoic Acid is used in the synthesis of selective METTL3 inhibitors. METTL3 is an enzyme that plays a critical role in RNA methylation, and its dysregulation is implicated in various cancers. Developing specific inhibitors can therefore offer new avenues for cancer therapy. For scientists working in these cutting-edge areas, sourcing this intermediate from a reliable manufacturer is a crucial first step.

Procuring 4-Bromo-2,5-difluorobenzoic Acid: What Buyers Need to Know

When considering the purchase of 4-Bromo-2,5-difluorobenzoic Acid, it is important for procurement specialists to focus on key specifications. Beyond the CAS number 28314-82-1 and a minimum purity of 97%, understanding the compound's physical properties, such as its light yellow powder appearance, is also important. For effective sourcing, engage with manufacturers who can provide comprehensive technical documentation and a stable supply chain. Many pharmaceutical companies opt to buy from Chinese suppliers due to their advanced chemical manufacturing capabilities and competitive pricing. Ensure your chosen supplier can offer timely delivery and responsive customer support, making the procurement process smooth and efficient.