For researchers and procurement managers in the pharmaceutical sector, securing high-quality chemical intermediates is paramount to successful drug discovery and development. One such critical compound is 4-Bromo-2,5-difluorobenzoic Acid, identified by its CAS number 28314-82-1. This article explores why this fluorinated benzoic acid derivative is a sought-after building block and how to find reliable manufacturers and suppliers for your needs.

The Importance of 4-Bromo-2,5-difluorobenzoic Acid in Synthesis

4-Bromo-2,5-difluorobenzoic Acid is a versatile intermediate widely utilized in organic synthesis, particularly within the pharmaceutical industry. Its unique structure, featuring bromine and fluorine atoms on a benzoic acid core, makes it an ideal starting material for creating complex organic molecules. Research indicates its significant role in the preparation of various biologically active compounds. For instance, it is a key intermediate in the synthesis of GPR119 agonists, which are compounds being explored for their potential in treating metabolic disorders and diabetes. Furthermore, it plays a role in the development of selective METTL3 inhibitors, an area of intense research in oncology.

Key Considerations When Buying This Intermediate

When you decide to buy 4-Bromo-2,5-difluorobenzoic Acid, purity is a non-negotiable factor. With a minimum purity of 97% commonly specified, ensuring a reliable supply chain from a reputable manufacturer is essential. Procurement managers often look for suppliers in China due to competitive pricing and robust manufacturing capabilities. Understanding the synthesis methods can also be beneficial, as variations in preparation can impact the final product's characteristics. The compound’s physical appearance is typically described as a light yellow powder, a detail confirmed by many suppliers.

Finding a Reliable Supplier

Identifying a trusted manufacturer and supplier for pharmaceutical intermediates like 4-Bromo-2,5-difluorobenzoic Acid is critical. Companies that provide Certificates of Analysis (CoA), detailed technical data sheets, and consistent product quality are preferred. Look for suppliers who can offer competitive pricing for bulk purchases and provide timely delivery. Many global buyers source such intermediates from China, partnering with manufacturers that have established expertise in fine chemical production and adhere to international quality standards. If you are seeking to buy this compound, explore suppliers who can offer samples for quality assurance and demonstrate a commitment to customer service, ensuring you get the best price and product.