While 2-(4-Bromomethyl)phenylpropionic Acid (CAS: 111128-12-2) is widely recognized for its crucial role as an intermediate in the synthesis of the NSAID Loxoprofen, its chemical utility extends much further. As a versatile organic building block, this compound offers significant potential for chemists and researchers in various fields of chemical synthesis. Understanding its inherent reactivity can unlock new pathways for innovation, making it a valuable commodity for purchase from reliable suppliers.

The Reactive Bromomethyl Group: A Gateway to Synthesis

The defining feature of 2-(4-Bromomethyl)phenylpropionic Acid is its bromomethyl group (-CH2Br). This electrophilic site makes the molecule highly susceptible to nucleophilic substitution reactions. This reactivity is fundamental to its use in:

  • Bromomethylation Reactions: The compound can efficiently introduce a bromomethyl group onto various substrates. This is a common strategy in organic synthesis for functionalizing molecules, creating reactive handles for further modifications, or building more complex structures.
  • Coupling Reactions: Its aryl bromide functionality, though indirect through the methylene bridge, can be leveraged in palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings, allowing for the formation of new carbon-carbon bonds.
  • Grignard Reagent Formation: While direct Grignard formation might require specific conditions due to the presence of the carboxylic acid group, derivatization can enable the creation of organometallic reagents useful in C-C bond formation.

These properties make 2-(4-Bromomethyl)phenylpropionic Acid an attractive starting material for synthesizing a wide array of specialty chemicals, agrochemicals, and novel pharmaceutical candidates.

Sourcing for Advanced Chemical Synthesis

For researchers and manufacturers looking to explore these diverse applications, sourcing high-quality 2-(4-Bromomethyl)phenylpropionic Acid is key. As a leading chemical manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. provides this compound with guaranteed high purity (≥97%) and consistent specifications. Our ability to supply this intermediate in various quantities ensures that whether you are conducting small-scale laboratory research or large-scale industrial synthesis, you have access to a dependable source.

Partnering for Innovation

We encourage chemists and product developers to consider 2-(4-Bromomethyl)phenylpropionic Acid for their next synthesis project. Its versatile reactivity, coupled with our commitment to quality and competitive pricing, makes it an excellent choice for innovation. If you are looking to buy this chemical for applications beyond Loxoprofen synthesis, or simply need a reliable supplier for your ongoing needs, we invite you to contact us for a quote and to discuss your specific requirements. Unlock the full potential of this valuable chemical intermediate with a trusted partner.