The pharmaceutical industry relies heavily on precisely synthesized intermediates to produce life-enhancing medications. For professionals in research and development, understanding the chemical pathways and crucial building blocks is essential. One such critical compound is 2-(4-Bromomethyl)phenylpropionic Acid (CAS: 111128-12-2), a key intermediate in the synthesis of Loxoprofen, a widely used non-steroidal anti-inflammatory drug (NSAID).

Unpacking the Chemical Structure and Properties

2-(4-Bromomethyl)phenylpropionic Acid is a propionic acid derivative characterized by a bromomethyl group attached to a phenyl ring, which also carries a propionic acid moiety. This specific structure imparts unique reactivity, making it an ideal candidate for pharmaceutical synthesis. Typically appearing as a white to off-white crystalline powder, its purity levels are often a primary concern for buyers. Reputable manufacturers, like us at NINGBO INNO PHARMCHEM CO.,LTD., ensure that this intermediate meets stringent quality standards, often exceeding 97% purity, with consistent physical properties such as a melting point in the range of 126-130°C.

2-(4-Bromomethyl)phenylpropionic Acid in Loxoprofen Synthesis

The primary application of 2-(4-Bromomethyl)phenylpropionic Acid is its function as a precursor in the multi-step synthesis of Loxoprofen. The bromomethyl group serves as a reactive handle for subsequent chemical transformations, ultimately leading to the active pharmaceutical ingredient (API). The efficiency and success of Loxoprofen production are directly tied to the quality and availability of this intermediate. Therefore, sourcing from a dependable manufacturer and supplier in China is crucial for maintaining a stable and cost-effective production line.

Applications Beyond Loxoprofen

While its role in Loxoprofen synthesis is most prominent, the inherent reactivity of 2-(4-Bromomethyl)phenylpropionic Acid also makes it valuable in other organic synthesis applications. Its bromomethyl group is amenable to various reactions, including bromomethylation, and it exhibits notable reactivity in coupling reactions such as Suzuki and Grignard reactions. This versatility allows researchers and chemists to explore its potential in developing novel compounds and specialty chemicals, making it a versatile chemical reagent for advanced synthetic chemistry.

Choosing the Right Supplier

When seeking to purchase 2-(4-Bromomethyl)phenylpropionic Acid, it is imperative to collaborate with a chemical supplier that prioritizes quality, reliability, and technical support. As a leading manufacturer in China, we are committed to providing high-purity intermediates with detailed technical specifications and responsive customer service. We understand the critical nature of pharmaceutical intermediates and ensure that our products contribute positively to your research and manufacturing endeavors. Contact us today to request a quote and discuss your supply needs for this essential chemical.