In the complex landscape of pharmaceutical manufacturing, the quality and reliability of chemical intermediates are of paramount importance. Bivalirudin, a synthetic peptide identified by its CAS number 128270-60-0, is a highly sought-after pharmaceutical intermediate due to its potent anticoagulant properties as a direct thrombin inhibitor (DTI). As a leading Bivalirudin manufacturer in China, we are dedicated to supplying this critical compound to the global pharmaceutical industry with exceptional purity and consistency.

What is Bivalirudin?

Bivalirudin is a synthetic analog of hirudin, a natural anticoagulant found in the saliva of medicinal leeches. It is a 20-amino acid peptide that directly inhibits thrombin, a key enzyme in the blood clotting cascade. Its mechanism involves binding to both the active site and the exosite of thrombin, rendering it inactive. This direct inhibition is reversible, contributing to its favorable safety profile, particularly in terms of reduced bleeding risk compared to other anticoagulants like heparin. Typically appearing as a white powder, Bivalirudin is characterized by its high purity, often exceeding 99.5%, making it ideal for pharmaceutical formulations.

Key Applications in the Pharmaceutical Industry

The primary therapeutic application for Bivalirudin is as an anticoagulant in cardiovascular medicine, especially during Percutaneous Coronary Intervention (PCI). It is used in patients undergoing procedures for unstable angina, non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI). Its ability to prevent thrombus formation while minimizing adverse bleeding events makes it a preferred choice for clinicians. Beyond direct therapeutic use, Bivalirudin also serves as a vital intermediate in the research and development of new anticoagulation strategies and related pharmaceutical products.

Why Choose a China Manufacturer for Bivalirudin?

For pharmaceutical companies, sourcing critical intermediates like Bivalirudin requires careful consideration of suppliers. China has emerged as a global leader in the production of fine chemicals and pharmaceutical intermediates, offering competitive pricing and robust manufacturing capabilities. When you choose to buy Bivalirudin CAS 128270-60-0 from a reputable China manufacturer, you gain access to:

  • High-Purity Products: Manufacturers like us adhere to strict quality control protocols to ensure Bivalirudin meets 99.5% minimum purity standards.
  • Cost-Effectiveness: Benefit from competitive pricing without compromising on quality.
  • Reliable Supply Chain: We ensure a consistent and dependable supply to support your production needs.
  • Technical Expertise: Our team possesses deep knowledge in peptide synthesis and pharmaceutical chemistry.

Conclusion

Bivalirudin (CAS 128270-60-0) is a critical component in modern cardiovascular medicine and a valuable pharmaceutical intermediate. By selecting a trusted Bivalirudin supplier in China, you can ensure the quality, availability, and cost-effectiveness necessary for successful pharmaceutical development and manufacturing. We are committed to being your premier partner for high-purity Bivalirudin, contributing to advancements in cardiovascular health.