Bivalirudin, identified by CAS number 128270-60-0, is a sophisticated synthetic peptide that has become indispensable in modern medicine, particularly in the realm of anticoagulation. As a direct thrombin inhibitor (DTI), it offers a highly specific and reversible mechanism for managing thrombotic risks, especially in interventional cardiology. Understanding its properties and applications is crucial for procurement managers and R&D scientists in the pharmaceutical sector.

Chemical Profile and Key Properties

Bivalirudin is a 20-amino acid peptide with a molecular weight of approximately 2180.3 g/mol. Its physical appearance is typically a white powder, indicating high purity suitable for pharmaceutical use. Key specifications often include an assay of 99.5% minimum, ensuring minimal impurities that could affect its therapeutic efficacy or safety profile. The molecule's structure allows it to bind potently and specifically to thrombin, both in circulation and when bound to a thrombus. This direct inhibition is a significant advantage, as it does not require co-factors like antithrombin and bypasses the risks associated with heparin, such as heparin-induced thrombocytopenia.

Therapeutic Applications and Clinical Significance

The primary application of Bivalirudin lies in its role as an anticoagulant during percutaneous coronary interventions (PCI). It is frequently used in patients with unstable angina, non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI). Studies consistently show that Bivalirudin provides effective anticoagulation while significantly reducing the incidence of bleeding compared to traditional heparin-based therapies. This favorable safety profile makes it a preferred choice for physicians and a valuable product for pharmaceutical companies. The ability to buy Bivalirudin from a reliable China manufacturer ensures that these life-saving treatments are accessible.

The Value of Sourcing from a Proven Manufacturer

For pharmaceutical procurement, consistency and quality are paramount. When seeking to purchase Bivalirudin CAS 128270-60-0, partnering with an experienced Bivalirudin supplier in China offers significant advantages. These suppliers are equipped with advanced manufacturing processes and rigorous quality control measures to guarantee high-purity products. We understand the critical nature of pharmaceutical intermediates and are committed to providing Bivalirudin that meets stringent international standards. Our offerings ensure that your research and manufacturing processes benefit from a dependable supply of this vital compound.

Conclusion

Bivalirudin (CAS 128270-60-0) is a cornerstone in modern anticoagulation therapy, offering a safer and more effective alternative in many clinical scenarios. Its efficacy as a direct thrombin inhibitor, coupled with its favorable safety profile, makes it an essential pharmaceutical intermediate. By choosing a reputable Bivalirudin manufacturer in China, you secure access to a high-quality product backed by stringent quality assurance and a stable supply chain. We invite you to inquire about our Bivalirudin offerings and experience the difference that reliable sourcing makes.