In the realm of advanced organic synthesis, particularly within peptide chemistry, the selection of protected amino acid derivatives is a cornerstone of successful research and development. Boc-His(Bom)-OH, identified by its CAS number 79950-65-5, is a highly valued intermediate. As a protected form of histidine, it offers the necessary chemical handles for precise peptide chain elongation. This article highlights the significance of Boc-His(Bom)-OH for researchers and procurement specialists seeking a reliable chemical supplier for their synthetic needs.

Histidine is a unique amino acid, characterized by its imidazole side chain, which is crucial for the biological activity of many peptides and proteins. Protecting this side chain, along with the alpha-amino group, is essential during multi-step synthesis to prevent unwanted reactions. The N-tert-butyloxycarbonyl (Boc) group effectively safeguards the alpha-amino terminus, while the N-benzyloxymethyl (Bom) group provides robust protection for the imidazole ring. This specific protection strategy makes Boc-His(Bom)-OH a preferred choice for numerous peptide synthesis protocols, including those employing Boc-based solid-phase peptide synthesis (SPPS).

For professionals in the pharmaceutical and biotechnology sectors, understanding the chemical properties and sourcing options for Boc-His(Bom)-OH is paramount. Its stability, solubility in common organic solvents like DMF and DCM, and its role as a high-purity intermediate are key considerations. When you decide to purchase Boc-His(Bom)-OH, seeking out a reputable manufacturer and supplier is vital. We, as a dedicated manufacturer, ensure that our product meets stringent purity criteria, making it an ideal raw material for your demanding applications. We focus on providing a consistent supply of this critical compound, catering to the needs of R&D scientists and procurement managers who require dependable chemical sources.

The utility of Boc-His(Bom)-OH is evident in its broad application spectrum. It is indispensable for synthesizing peptides that mimic natural hormones, enzymes, or antibodies, as well as for creating novel peptide-based therapeutics. The imidazole side chain's ability to participate in hydrogen bonding, metal coordination, and acid-base catalysis can be precisely controlled when this protected derivative is used. This level of control is what enables the creation of peptides with tailored biological functions and improved pharmacokinetic profiles.

When engaging with chemical suppliers, looking for those who offer comprehensive product information, including detailed specifications and certificates of analysis, is recommended. As a manufacturer, we are committed to transparency and quality assurance, providing all necessary documentation to support your decision to buy Boc-His(Bom)-OH from us. Whether you are in the early stages of drug discovery or scaling up peptide production, our commitment to excellence as a supplier ensures you receive a product that meets your exact specifications, backed by competitive pricing and reliable delivery.