In the intricate world of peptide synthesis, precision and reliability are non-negotiable. Amino acid derivatives serve as the fundamental building blocks, and understanding their specific properties is key to successful peptide chain elongation. Among these, N2-Boc-N6-acetyl-L-lysine, often abbreviated as Boc-Lys(Ac)-OH (CAS: 6404-26-8), stands out as a valuable tool for chemists. As a leading manufacturer and supplier, we are dedicated to providing researchers and industries with high-quality materials like Boc-Lys(Ac)-OH to support their scientific endeavors.

What is Boc-Lys(Ac)-OH?

Boc-Lys(Ac)-OH is a derivative of L-lysine, an essential amino acid. The tert-butyloxycarbonyl (Boc) group is a common acid-labile protecting group for the alpha-amino function, while the acetyl (Ac) group serves as a stable protection for the epsilon-amino group on the lysine side chain. This orthogonal protection scheme is highly advantageous in solid-phase peptide synthesis (SPPS) and solution-phase synthesis, allowing for selective manipulation of the amino groups at different stages of the synthetic process. Chemically, it has the formula C13H24N2O5 and a molecular weight of 288.34 g/mol. It typically presents as a white powder.

Applications in Peptide Chemistry

The primary utility of Boc-Lys(Ac)-OH lies in its role as a protected amino acid in peptide synthesis. Its presence allows chemists to build peptides with specific lysine modifications or to incorporate lysine in complex sequences where differential protection is critical. This is particularly relevant for:

  • Synthesis of complex peptides: Where selective functionalization of the side chain is required.
  • Peptide conjugation: Attaching peptides to carriers, labels, or other molecules via the lysine side chain.
  • Research into protein modifications: Mimicking natural lysine modifications like acetylation.

By providing robust protection that can be selectively removed, Boc-Lys(Ac)-OH facilitates the creation of precisely engineered peptide sequences for therapeutic, diagnostic, and research applications.

Ensuring Quality from a Manufacturer and Supplier

For any laboratory or manufacturing facility, the consistent quality of chemical reagents is crucial. As a dedicated supplier of fine chemical intermediates, we emphasize the importance of purity and reliable sourcing. When you choose to buy Boc-Lys(Ac)-OH from a reputable manufacturer, you are investing in the success of your synthesis. We ensure that our product meets stringent quality control parameters, verified through analytical techniques, to guarantee its suitability for demanding peptide synthesis protocols. Sourcing from a trusted manufacturer in China means you benefit from competitive pricing and a stable supply chain, essential for both research projects and larger-scale production.

Whether you are developing novel peptide-based therapeutics or conducting advanced biochemical research, having access to high-quality Boc-Lys(Ac)-OH is indispensable. We are committed to being your reliable partner, providing the essential building blocks needed to drive innovation in your work.