The field of peptide synthesis is at the forefront of pharmaceutical research, enabling the development of novel therapeutics and biomaterials. Within this specialized area, chiral building blocks like Boc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid (CAS: 269396-59-0) are indispensable. Understanding its properties and applications can significantly aid researchers in optimizing their synthesis strategies and achieving desired molecular outcomes. As a leading manufacturer, we are dedicated to providing scientists with the highest quality intermediates to facilitate groundbreaking work.

The Significance of Boc Protection and Chirality

Boc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid is characterized by two key features crucial for peptide synthesis: the tert-butyloxycarbonyl (Boc) protecting group and its specific (R) chirality. The Boc group is a widely used amine protecting group in solid-phase peptide synthesis (SPPS), allowing for selective deprotection under mild acidic conditions. This selective removal is vital for controlling the stepwise addition of amino acids, preventing unwanted side reactions, and ensuring the integrity of the growing peptide chain. The compound's defined (R) stereochemistry is equally important, as the biological activity of peptides is highly dependent on their precise three-dimensional structure. Utilizing enantiomerically pure building blocks like this ensures the synthesis of peptides with the correct spatial orientation and biological function.

Advantages of the 3,4-Difluorophenyl Moiety

The inclusion of a 3,4-difluorophenyl group in this amino acid derivative offers distinct advantages. Fluorine atoms are known to significantly alter the electronic properties, lipophilicity, metabolic stability, and binding affinities of organic molecules. In peptide design, incorporating fluorinated amino acids can lead to enhanced proteolytic resistance, improved membrane permeability, and stronger interactions with target proteins. This makes Boc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid a valuable tool for researchers aiming to develop peptides with superior pharmacological profiles, such as increased bioavailability or longer half-lives in vivo. For those looking to buy this compound for peptide applications, seeking a supplier that guarantees its consistent quality and accurate stereochemistry is essential.

Sourcing and Procurement for Peptide Synthesis

As a dedicated manufacturer and supplier of specialized chemicals, we understand the critical need for reliable, high-purity intermediates for peptide synthesis. We offer Boc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid with a minimum purity of 97%, ensuring it meets the rigorous demands of peptide chemists. Our manufacturing processes in China are optimized for efficiency and quality control, allowing us to provide this essential building block at competitive prices. Whether you are synthesizing therapeutic peptides, diagnostic tools, or research peptides, sourcing your materials from a trusted manufacturer like us guarantees consistency and performance. We encourage peptide synthesis specialists to inquire about our product specifications and discuss their bulk purchasing needs.

Inquiry and Next Steps

To integrate Boc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid into your peptide synthesis workflow, we invite you to contact us. We are committed to supporting the scientific community by providing high-quality chemical intermediates. Explore our offerings and discover how our reliable supply chain and dedication to excellence can accelerate your research and development efforts. Request a quote or sample today to experience the quality and service that makes us a preferred supplier for critical research chemicals.