In the realm of chemical research and development, the availability of well-defined molecular building blocks is crucial for innovation. Heterocyclic compounds, particularly pyridine derivatives, are foundational to many advanced materials, pharmaceuticals, and agrochemicals. Among these, 2-Chloro-3-pyridinamine (CAS 6298-19-7) stands out as a versatile and important intermediate. This article provides an overview of its properties, applications, and the importance of sourcing it from reliable manufacturers, especially those based in China.

What is 2-Chloro-3-pyridinamine?

2-Chloro-3-pyridinamine, also known by synonyms such as 2-chloro-3-aminopyridine, is characterized by its pyridine ring substituted with a chlorine atom at the 2-position and an amine group at the 3-position. Its molecular formula is C5H5ClN2, and it has a molecular weight of 128.56 g/mol. Typically supplied as an off-white to yellow to pink crystalline powder, it is highly valued for its purity, often exceeding 99%, which is critical for downstream synthetic processes.

Key Applications and Chemical Utility

The dual functionality of 2-Chloro-3-pyridinamine makes it a highly sought-after intermediate in several key industries:

  • Pharmaceutical Synthesis: It serves as a core component in the synthesis of various Active Pharmaceutical Ingredients (APIs) and their intermediates. The pyridine scaffold is a common motif in many therapeutic agents.
  • Agrochemical Development: The compound is utilized in the creation of novel crop protection agents, including herbicides and insecticides, contributing to the efficiency and specificity of agricultural treatments.
  • Organic Synthesis and Research: Its structure lends itself to various chemical transformations, most notably palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling. This allows chemists to efficiently create complex carbon-carbon bonds, vital for creating new molecular entities.

The Advantage of Sourcing from China

For researchers and chemical procurement specialists, sourcing intermediates like 2-Chloro-3-pyridinamine from China offers significant advantages. Chinese manufacturers are renowned for their large-scale production capabilities, competitive pricing, and growing expertise in complex organic synthesis. When you look to buy this chemical, partnering with a reputable Chinese supplier ensures access to high-purity material, consistent quality control, and reliable supply chains. This is particularly important for R&D projects where material consistency is key.

Procurement Tips for Buyers

When sourcing 2-Chloro-3-pyridinamine (CAS 6298-19-7), it is advisable to:

  • Confirm the supplier's ability to provide material with a purity of ≥99%.
  • Request product specifications and Safety Data Sheets (SDS).
  • Inquire about lead times and shipping options for timely delivery.
  • Obtain quotes for different quantities, especially if bulk purchases are anticipated.

Conclusion

2-Chloro-3-pyridinamine is more than just a chemical compound; it is a fundamental building block that empowers innovation in the pharmaceutical, agrochemical, and broader chemical industries. Its versatility and the advantages of sourcing from established Chinese manufacturers make it an accessible and valuable resource for R&D professionals. We are a leading producer and supplier, committed to delivering high-quality 2-chloro-3-pyridinamine to support your chemical synthesis needs. Contact us today to inquire about pricing and availability.