In the vast landscape of chemical compounds, certain molecules serve as foundational elements for significant advancements in various industries. 2-Chloro-3-pyridinamine (CAS 6298-19-7) is one such compound, recognized for its critical role as an intermediate in the pharmaceutical and agrochemical sectors, as well as a versatile reagent in organic synthesis. This article aims to provide a comprehensive understanding of this pyridine derivative, including its properties, applications, and a guide on how to procure it efficiently.

Understanding 2-Chloro-3-pyridinamine

Also known by its synonyms like 2-chloro-3-aminopyridine or 3-amino-2-chloropyridine, 2-Chloro-3-pyridinamine is a heterocyclic organic compound. Its chemical formula is C5H5ClN2, and it possesses a molecular weight of 128.56 g/mol. Physically, it is typically described as an off-white to yellow to pink crystalline powder. A key attribute for its industrial use is its high purity, often exceeding 99%, which is essential for reliable downstream synthesis.

Key Properties and Chemical Utility

The chemical structure of 2-Chloro-3-pyridinamine makes it highly valuable:

  • Functional Groups: It features an amine group (-NH2) and a chlorine atom (-Cl) attached to a pyridine ring. This dual functionality allows for diverse chemical reactions.
  • Reactivity: The chlorine atom on the pyridine ring is particularly reactive in palladium-catalyzed cross-coupling reactions, such as the widely utilized Suzuki-Miyaura coupling. This reaction is fundamental for forming carbon-carbon bonds in complex molecular structures.
  • Building Block: It serves as a crucial building block for synthesizing more complex molecules, including active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Major Application Areas

The versatility of 2-Chloro-3-pyridinamine leads to its application in several critical fields:

  • Pharmaceuticals: It is an essential intermediate in the synthesis of various drugs, contributing to the development of new therapeutic agents.
  • Agrochemicals: It is used in the formulation of herbicides, insecticides, and fungicides, helping to improve crop protection and agricultural yields.
  • Organic Synthesis: Researchers utilize it in laboratory settings for creating novel compounds and exploring new synthetic methodologies.

How to Buy 2-Chloro-3-pyridinamine

Procuring 2-Chloro-3-pyridinamine (CAS 6298-19-7) requires careful selection of suppliers. Here are key steps for buyers:

  • Identify Reliable Suppliers: Look for manufacturers and distributors with a strong track record, offering products with guaranteed purity (e.g., ≥99%). Websites of chemical suppliers often provide detailed product information, including CAS numbers, molecular formulas, and physical properties.
  • Obtain Quotes and Specifications: Request quotes for the desired quantity. Always ask for a Certificate of Analysis (CoA) to verify purity and compliance with specifications.
  • Consider Manufacturers in China: Chinese chemical manufacturers are globally recognized for their capacity to produce high-quality intermediates at competitive prices, making them an excellent option for bulk purchases.
  • Understand Lead Times and Logistics: Confirm shipping options, delivery times, and any necessary import documentation to ensure timely receipt of the material.

Conclusion

2-Chloro-3-pyridinamine is a vital chemical intermediate that facilitates innovation in critical industries. Understanding its properties and how to source it effectively, particularly from reputable manufacturers, is key for R&D professionals and procurement managers. We are a dedicated supplier of high-purity 2-Chloro-3-pyridinamine, committed to providing exceptional products and service. Contact us today to get a quote for your chemical needs.