For procurement professionals in the pharmaceutical industry, sourcing critical intermediates like (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone (CAS 141645-16-1) involves a strategic evaluation process. This compound is a vital intermediate in the production of Dronedarone, a medication essential for patients with specific cardiac conditions. Ensuring a consistent and reliable supply of this high-quality chemical is paramount to maintaining uninterrupted drug manufacturing.

When initiating a purchase, the first step is to identify reputable manufacturers and suppliers. Given its application in pharmaceuticals, seeking out suppliers who specialize in fine chemicals and pharmaceutical intermediates is crucial. These suppliers typically offer products with guaranteed high purity, often exceeding 99%, and provide comprehensive documentation, including Certificates of Analysis (CoA) detailing impurity profiles, moisture content, and other critical specifications. For (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone, key specifications include a minimum purity of ≥99%, and impurity levels ≤0.2%.

Price is naturally a significant consideration for any procurement manager. However, it should be balanced against quality and reliability. While manufacturers in China often offer competitive pricing for chemical intermediates, it’s important to look beyond the lowest quote. A supplier’s track record, manufacturing standards, and ability to provide consistent quality are more important long-term. Requesting quotes from multiple established suppliers is a good practice to gauge market rates and identify potential partners who offer the best value for money when you buy this Dronedarone intermediate.

Beyond price and purity, other factors to consider include packaging and shipping. The standard 25kg cardboard drum is common, but inquiring about customized packaging solutions can be beneficial for specific manufacturing setups. Understanding the supplier's shipping capabilities, especially for international orders, and their adherence to regulatory compliance for hazardous materials (though this compound is generally not classified as hazardous) is also vital. By systematically evaluating these aspects, procurement professionals can secure a dependable source for (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone, ensuring the continuity of Dronedarone production.