For professionals in the pharmaceutical industry, the procurement of intermediates is a critical step that directly influences the quality and cost-effectiveness of the final drug product. Febuxostat, a leading medication for gout and hyperuricemia, relies on specific chemical precursors for its synthesis. One such essential intermediate is Ethyl 2-[4-(2-methylpropoxy)-3-nitrophenyl]-1,3-thiazole-5-carboxylate, identified by CAS number 144060-93-5. This article outlines key considerations for anyone looking to buy this vital chemical compound, emphasizing quality, specifications, and sourcing from reputable manufacturers.

Essential Quality Parameters for 144060-93-5

When purchasing any pharmaceutical intermediate, prioritizing quality is paramount. For Ethyl 2-[4-(2-methylpropoxy)-3-nitrophenyl]-1,3-thiazole-5-carboxylate, these parameters are particularly important:

  • Assay/Purity: The intermediate must meet a high purity standard, typically ≥98.0%, to ensure that the synthesis of Febuxostat proceeds without generating undesirable byproducts. Impurities at this stage can lead to complex purification challenges downstream and potentially affect the final API's efficacy and safety.
  • Physical Appearance: The compound is usually supplied as a white to off-white crystalline powder. Consistency in this physical form is an indicator of reliable manufacturing processes and can impact handling and reaction kinetics.
  • Chemical Identity: Confirming the chemical identity through CAS number and proper nomenclature is crucial. Reputable suppliers will provide detailed Certificates of Analysis (CoA) that confirm the product's identity and purity.
  • Packaging and Storage: Adequate packaging, such as 25 kg drums, and adherence to recommended storage conditions are vital for maintaining the intermediate's stability and shelf life.

Choosing a Reliable Supplier: Focus on Manufacturers in China

China has become a leading global supplier for pharmaceutical intermediates, offering both competitive pricing and a wide selection of manufacturers. When you decide to buy Ethyl 2-[4-(2-methylpropoxy)-3-nitrophenyl]-1,3-thiazole-5-carboxylate from China, consider the following:

  • Supplier Reputation and Track Record: Research the supplier's history, customer reviews, and any certifications they may hold. A proven track record in supplying the pharmaceutical industry is a significant advantage.
  • Manufacturing Capabilities: Ensure the manufacturer has the capacity and technical expertise to consistently produce the intermediate to your required specifications.
  • Quality Control Systems: A manufacturer with robust in-house quality control and quality assurance processes is essential. They should be able to provide detailed CoAs for every batch.
  • Pricing and Lead Times: Obtain quotes from multiple suppliers to compare pricing. Also, clarify lead times for delivery, including potential shipping and customs processing.
  • Technical Support: A supplier that can offer technical assistance or documentation can be a valuable partner in your development process.

Partnering with Us for Your Febuxostat Intermediate Needs

As an experienced manufacturer and supplier of high-quality pharmaceutical intermediates, we are dedicated to providing reliable access to Ethyl 2-[4-(2-methylpropoxy)-3-nitrophenyl]-1,3-thiazole-5-carboxylate. We understand the critical importance of purity, consistency, and timely delivery for our clients. Our state-of-the-art manufacturing facilities in China, coupled with rigorous quality control measures, ensure that you receive a product that meets your exact specifications. We invite you to experience the benefits of partnering with a trusted supplier committed to your success. When you need to buy this essential Febuxostat intermediate, we are your premier choice.

To inquire about pricing, availability, or to place an order for Ethyl 2-[4-(2-methylpropoxy)-3-nitrophenyl]-1,3-thiazole-5-carboxylate, please contact our sales team. We look forward to supporting your pharmaceutical manufacturing endeavors.