The Chemical Profile of 1-Benzothiophene-5-carboxylic Acid: Properties and Applications
In the realm of fine chemicals and pharmaceutical intermediates, compounds with unique structural features are highly sought after for their potential to unlock new synthetic possibilities. 1-Benzothiophene-5-carboxylic Acid (CAS: 2060-64-2) is one such molecule, offering a robust scaffold for a variety of chemical transformations. Understanding its chemical profile, including physical and chemical properties, is essential for researchers and chemists looking to leverage its capabilities in their work. This overview highlights what makes this compound a valuable asset in the laboratory and industry.
1-Benzothiophene-5-carboxylic Acid, with its chemical identity defined by CAS number 2060-64-2, molecular formula C9H6O2S, and molecular weight of 178.21 g/mol, presents as a white solid. Its physical attributes include a significant melting point, typically recorded between 207-208°C, indicating a stable crystalline structure. Chemically, the presence of a carboxylic acid group (-COOH) makes it an acidic compound, with a predicted pKa of around 4.13. This functional group is highly reactive and can participate in various reactions such as esterification, amidation, and salt formation. The fused benzothiophene ring system itself offers sites for electrophilic aromatic substitution and other modifications, further expanding its synthetic utility.
The principal utility of 1-Benzothiophene-5-carboxylic Acid lies in its role as an intermediate in organic synthesis, particularly within the pharmaceutical sector. It serves as a critical building block for the construction of complex molecules, including active pharmaceutical ingredients (APIs), specialty chemicals, and materials with unique properties. Its incorporation into synthetic pathways allows for the introduction of the benzothiophene moiety, which is found in numerous biologically active compounds. Researchers often look to buy 1-benzothiophene-5-carboxylic acid to explore novel therapeutic agents or to develop new functional materials.
When sourcing this intermediate, consider partnering with reputable chemical suppliers who can guarantee high purity, typically 95% or above. As a leading manufacturer and supplier, companies based in China often provide excellent value, combining quality with competitive pricing. To find the best source, search for terms like '1-Benzothiophene-5-carboxylic acid price' or 'CAS 2060-64-2 for sale'. Engaging with a reliable supplier ensures access to detailed product specifications, analytical data, and safety information, facilitating efficient procurement and safe handling. Furthermore, checking for availability of bulk quantities can be beneficial for larger projects.
The stability of 1-Benzothiophene-5-carboxylic Acid under ambient conditions simplifies its storage and handling, making it a practical choice for laboratory use. However, as with any chemical, consulting the Material Safety Data Sheet (MSDS) for specific safety precautions is always recommended. For those looking to purchase this intermediate, understanding the range of applications and the supplier's capacity to meet demand is crucial. A strong supplier relationship can guarantee a steady flow of this essential building block, supporting uninterrupted research and production.
In conclusion, 1-Benzothiophene-5-carboxylic Acid is a chemically versatile and synthetically valuable intermediate. Its well-defined properties and broad applicability make it a key component in many advanced chemical synthesis projects. By carefully selecting a trusted supplier and understanding the compound's profile, researchers and manufacturers can effectively utilize this important building block to drive innovation.
Perspectives & Insights
Future Origin 2025
“The fused benzothiophene ring system itself offers sites for electrophilic aromatic substitution and other modifications, further expanding its synthetic utility.”
Core Analyst 01
“The principal utility of 1-Benzothiophene-5-carboxylic Acid lies in its role as an intermediate in organic synthesis, particularly within the pharmaceutical sector.”
Silicon Seeker One
“It serves as a critical building block for the construction of complex molecules, including active pharmaceutical ingredients (APIs), specialty chemicals, and materials with unique properties.”