(R)-(+)-1-Phenylethylamine, identified by its CAS number 3886-69-9, is a compound of significant interest across various sectors of the chemical industry, particularly in pharmaceuticals and fine chemical synthesis. Understanding its comprehensive chemical profile—from physical properties to reactivity and specific applications—is crucial for R&D scientists and procurement professionals aiming to source this vital chiral amine effectively.

Chemical Identity and Properties

The compound's chemical formula is C8H11N, with a molar mass of approximately 121.18 g/mol. Key physical and chemical properties commonly reported include:

  • Appearance: Typically a clear, colorless to pale yellow liquid.
  • Assay (Purity): High purity is essential, with specifications often set at ≥99.0%.
  • Boiling Point: Approximately 187-189 °C at standard atmospheric pressure.
  • Melting Point: Around -10 °C, indicating its liquid state at room temperature.
  • Density: Typically around 0.952 g/mL at 20 °C.
  • Refractive Index: Commonly listed as n20/D 1.526.
  • Specific Rotation: This is a critical parameter for chiral compounds, with values often around +38° to +40° (neat at 20°C or 25°C).
  • Flash Point: Around 70-75 °C, indicating moderate flammability.

These properties dictate its handling, storage, and reactivity in various chemical processes.

Applications: More Than Just a Resolving Agent

While (R)-(+)-1-Phenylethylamine is renowned for its role as a chiral resolving agent, its utility extends further:

  • Chiral Resolution: Its primary application involves forming diastereomeric salts with chiral acids, allowing for the separation and purification of individual enantiomers. This is fundamental in the production of enantiomerically pure pharmaceuticals and other optically active compounds.
  • Pharmaceutical Intermediates: It serves as a key chiral building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its specific stereochemistry can be incorporated into drug molecules to impart the desired pharmacological activity.
  • Organic Synthesis: The amine functionality and the chiral center make it a versatile reagent for asymmetric synthesis, contributing to the development of novel molecules with specific spatial arrangements.

Procuring High-Quality (R)-(+)-1-Phenylethylamine

For researchers and manufacturers looking to buy (R)-(+)-1-Phenylethylamine, ensuring quality and reliability is paramount. Sourcing from established chemical manufacturers and suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., guarantees that the product meets stringent specifications. These suppliers provide necessary documentation, including Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), along with competitive pricing and efficient logistics. Engaging with such suppliers ensures that your synthetic pathways and analytical methods are supported by consistently high-quality materials.

We invite you to explore the benefits of using (R)-(+)-1-Phenylethylamine in your operations. Contact us for more information or to request a quote for your specific needs.