In the realm of chemical synthesis, understanding the intrinsic properties of a compound is the first step towards its successful application. 4-Nitro-L-phenylalanine Methyl Ester Hydrochloride (CAS: 17193-40-7), a derivative of the naturally occurring amino acid phenylalanine, possesses a unique set of characteristics that make it valuable across various scientific disciplines. For researchers and procurement specialists seeking to buy this compound, a thorough understanding of its chemical profile is essential.

Key Chemical Characteristics of H-Phe(4-NO2)-OMe.HCl:

Let's explore the core chemical attributes that define 4-Nitro-L-phenylalanine Methyl Ester Hydrochloride:

  • Molecular Structure: The molecule is characterized by a phenylalanine backbone, featuring a methyl ester at the carboxyl group and a nitro group (NO2) attached to the para position of the phenyl ring. It is typically supplied as a hydrochloride salt, which enhances its stability and handling properties.
  • Molecular Formula and Weight: Its chemical formula is C10H13ClN2O4, with a molecular weight of approximately 260.67 g/mol. This precise molecular weight is crucial for stoichiometric calculations in synthesis.
  • Purity and Appearance: Reputable suppliers, such as manufacturers in China, often provide this compound with a purity of ≥98% (typically determined by HPLC). It generally appears as a white to off-white crystalline powder.
  • Reactivity of the Nitro Group: The nitro group is a strong electron-withdrawing substituent. This influences the electron density of the aromatic ring, making it more susceptible to nucleophilic aromatic substitution reactions. Conversely, it deactivates the ring towards electrophilic aromatic substitution. The nitro group can also be readily reduced to an amine group using various reducing agents, a transformation that is pivotal for further functionalization.
  • Chirality: As a derivative of L-phenylalanine, the alpha-carbon atom is chiral. The compound typically exists as the (S)-enantiomer, denoted by H-Phe(4-NO2)-OMe.HCl. Maintaining this chirality is vital for biological applications.
  • Stability and Storage: As a hydrochloride salt, it exhibits good stability. However, like many fine chemicals, it is best stored in a cool, dry place, often protected from light and moisture, to maintain its integrity over time. Suppliers will provide specific storage recommendations.

Significance for Research and Procurement:

The combination of a protected amino acid ester and a reactive nitro-aryl moiety makes H-Phe(4-NO2)-OMe.HCl a versatile intermediate. Researchers often seek to 'buy' or 'purchase' this compound from reliable 'manufacturers' or 'suppliers' in China because of the balance between quality, cost-effectiveness, and accessibility. Its predictable reactivity allows for its incorporation into complex organic synthesis routes for pharmaceuticals, agrochemicals, and advanced materials.

Understanding these chemical properties equips researchers with the knowledge to design effective synthesis strategies and select the most suitable suppliers. We are committed to providing detailed product information and high-quality chemicals to support your scientific endeavors.