1-Hydroxybenzotriazole (HOBt), identified by its CAS number 2592-95-2, is a chemical compound that holds significant importance across various scientific disciplines, particularly in organic and peptide synthesis. Its unique chemical properties make it an invaluable reagent for chemists and manufacturers. As a leading supplier of fine chemicals, we aim to shed light on the versatility and critical applications of HOBt, emphasizing the importance of sourcing from reputable manufacturers to ensure optimal performance.

Physically, HOBt typically presents as a white crystalline powder. Its chemical structure, a derivative of benzotriazole with a hydroxyl group attached to one of the nitrogen atoms, dictates its reactivity. HOBt is known for its role as a coupling reagent and, critically, as a racemization suppressor in peptide synthesis. It facilitates the formation of activated esters, which are key intermediates in creating amide bonds. This function is paramount for synthesizing complex peptides where maintaining stereochemical integrity is essential, such as in the development of pharmaceutical drugs.

Beyond peptide synthesis, HOBt is also utilized in broader organic chemistry applications. It can be employed in the synthesis of amides from carboxylic acids that are otherwise difficult to react. This broadens its applicability in creating diverse organic molecules. For companies looking to buy HOBt, understanding its properties, such as its solubility in various solvents and its stability, is crucial for designing efficient synthetic protocols. Partnering with a reliable chemical manufacturer ensures that the HOBt supplied meets precise specifications, including high purity (often exceeding 99.0%) and appropriate physical form.

The availability of HOBt from manufacturers in China offers a cost-effective solution for global procurement without compromising on quality. When considering HOBt for your applications, whether in academic research, pharmaceutical development, or other chemical industries, choosing a supplier with a strong track record is essential. We, as a dedicated chemical supplier, are committed to providing high-quality 1-Hydroxybenzotriazole that meets the rigorous demands of modern chemical synthesis, supporting your efforts to innovate and produce superior products.