1-Hydroxybenzotriazole (HOBt): A Crucial Reagent for Peptide Synthesis and Organic Chemistry

Discover the indispensable role of 1-Hydroxybenzotriazole (HOBt) in advancing peptide synthesis and complex organic chemical processes. As a leading supplier, we provide high-purity HOBt, essential for efficient amide bond formation and minimizing racemization, offering significant advantages for pharmaceutical and chemical manufacturers.

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Key Advantages of Sourcing 1-Hydroxybenzotriazole

Exceptional Racemization Suppression

Our 1-Hydroxybenzotriazole is a highly effective racemization inhibitor, essential for maintaining the enantiomeric purity of chiral molecules during peptide coupling, a critical factor for pharmaceutical synthesis.

Improved Synthesis Efficiency

By promoting the formation of activated esters, HOBt significantly boosts the efficiency of amide bond formation, allowing for faster and more reliable production cycles for peptide-based products.

High Purity and Quality Assurance

We are a dedicated supplier committed to providing 1-Hydroxybenzotriazole with rigorous quality control, ensuring ≥99.0% purity for consistent and predictable results in your research and manufacturing processes.

Applications Across Chemical Industries

Peptide Synthesis

The primary application of 1-Hydroxybenzotriazole is as a coupling reagent and racemization suppressor in both automated and solid-phase peptide synthesis, vital for creating therapeutic peptides and complex biomolecules.

Pharmaceutical Intermediates

Used in the synthesis and derivatization of polypeptide drug molecules and other bioactive compounds, making it a critical intermediate for the pharmaceutical manufacturing sector.

Organic Synthesis

Facilitates the formation of amide bonds from carboxylic acids that are not easily converted to acyl chlorides, offering a broad utility in diverse organic synthesis projects.

Cosmetic Formulations

HOBt can also be utilized in the production of cosmetics, adding another dimension to its application portfolio for chemical manufacturers and formulators.