For chemists, formulators, and procurement specialists in the chemical and pharmaceutical sectors, a thorough understanding of a compound's properties and applications is fundamental. 2-Amino-4-thiazoleacetic acid (CAS 29676-71-9) is one such versatile chemical, valued for its specific characteristics and its utility in various synthesis processes. This article explores the key chemical properties of 2-Amino-4-thiazoleacetic acid and highlights its significant applications, providing valuable insights for professionals looking to source or utilize this compound.

Key Chemical Properties and Specifications

2-Amino-4-thiazoleacetic acid typically presents as a white to yellowish or brown crystalline powder. Its physical form is important for handling and formulation processes. The compound has a defined melting point range, generally around 130°C with decomposition, which is a key indicator of its purity and thermal stability. With a molecular formula of C5H6N2O2S and a molecular weight of 158.18, it possesses reactive functional groups – an amine, a carboxylic acid, and a thiazole ring – that make it a useful building block in organic synthesis.

Suppliers and manufacturers often list additional properties such as solubility in various solvents. While it may have limited solubility in water, understanding its behavior in common organic solvents is crucial for researchers planning synthesis reactions. When you buy 2-amino-4-thiazoleacetic acid, always refer to the product's Material Safety Data Sheet (MSDS) and Certificate of Analysis (CoA) for detailed, lot-specific information on its physical and chemical characteristics.

Diverse Applications Across Industries

The primary and most significant application of 2-Amino-4-thiazoleacetic acid is its role as a critical intermediate in the pharmaceutical industry, particularly in the synthesis of Cefotiam, a broad-spectrum cephalosporin antibiotic. Its specific structure lends itself to building complex drug molecules efficiently. Beyond this major use, researchers in academic and industrial settings also explore its potential in:

  • Medicinal Chemistry: As a scaffold for developing novel therapeutic agents, leveraging the inherent biological activity potential of thiazole derivatives.
  • Organic Synthesis: As a versatile building block for creating a range of heterocyclic compounds and complex organic molecules.
  • Material Science: In some research contexts, it may be used in the development of novel polymers or functional materials.

For those looking to purchase 2-amino-4-thiazoleacetic acid for research and development or commercial production, understanding these diverse applications can inform purchasing decisions and potential future projects.

Sourcing High-Quality Material

Finding a reliable 2-amino-4-thiazoleacetic acid supplier is crucial for ensuring the success of any chemical synthesis project. Reputable manufacturers offer products with guaranteed purity levels (e.g., ≥98.0%) and consistent quality. When sourcing, particularly from international markets like China, it is advisable to request detailed specifications, inquire about storage conditions, and verify the supplier's commitment to quality control. As a recognized chemical intermediate, its availability from established chemical distributors ensures that researchers and manufacturers can readily access this important compound.

In essence, 2-Amino-4-thiazoleacetic acid is a valuable chemical entity owing to its well-defined properties and essential role, particularly in pharmaceutical synthesis. By understanding its characteristics and applications, professionals can make informed decisions when sourcing this key intermediate from trusted manufacturers and suppliers.