4-Methylbenzenesulfonhydrazide, identified by its CAS number 1576-35-8, is a chemical compound that holds significant importance in various fields of chemistry due to its distinct properties and reactivity. Commonly known by its shorter names such as p-Toluenesulfonhydrazide or Tosylhydrazide, this white to off-white powder serves as a crucial intermediate in organic synthesis and finds applications in pharmaceuticals and cosmetics.

Chemically, 4-Methylbenzenesulfonhydrazide features a sulfonyl hydrazide group attached to a toluene ring. This structure imparts specific chemical characteristics, including its solubility in water (approximately 5 g/L at 15°C) and its melting point, typically in the range of 103-108 °C. The presence of the sulfonyl group makes it moderately acidic, while the hydrazide portion offers nucleophilic properties, enabling it to react readily with electrophiles. This dual functionality is what makes it a versatile reagent for chemists aiming to buy and utilize it in their synthesis projects.

The primary application of 4-Methylbenzenesulfonhydrazide lies in its role as a reagent for the preparation of tosylhydrazones. These are formed through the condensation reaction between the hydrazide and aldehydes or ketones. Tosylhydrazones are valuable synthetic intermediates themselves, participating in reactions like the Shapiro reaction to form vinyl lithium species, or the Bamford-Stevens reaction for alkene synthesis. This makes the compound an essential purchase for laboratories involved in advanced organic chemistry research and for manufacturers producing complex organic molecules.

Beyond its use in tosylhydrazone formation, 4-Methylbenzenesulfonhydrazide is also employed in the synthesis of various heterocyclic compounds and has been noted for its use in the preparation of dipyrazolo[1,5-a:4',3'-c]pyridines and 1,2,3-selenadiazole derivatives. Its application in the pharmaceutical industry as a key intermediate in drug synthesis further amplifies its importance. For businesses looking to secure this chemical, identifying a reliable manufacturer and supplier that can provide consistent quality and supply is key.

We offer high-purity 4-Methylbenzenesulfonhydrazide, ensuring that our customers can achieve optimal results in their chemical synthesis endeavors. As a leading supplier from China, we pride ourselves on our commitment to quality and customer service. If your research or production requires this versatile chemical intermediate, we encourage you to reach out for a quote and learn more about how we can meet your needs. Buying from a trusted source is the first step towards successful synthesis.