N-Acetoxysuccinimide, identified by its CAS number 14464-29-0, is a compound of significant interest in the chemical industry due to its unique chemical properties and broad spectrum of applications. As a white crystalline powder, it stands out as a versatile reagent that facilitates complex chemical transformations, particularly in the realms of organic synthesis and bioconjugation.

Understanding the chemical properties of N-Acetoxysuccinimide is fundamental for its effective utilization. Its molecular formula is C6H7NO4, with a molecular weight of 157.12. A key characteristic is its classification as a succinimidyl ester, which imparts a specific reactivity pattern. The compound is known to be moisture-sensitive, a property that necessitates careful handling and storage to maintain its integrity and efficacy. Recommended storage conditions typically involve refrigeration and protection from humidity, often under an inert atmosphere. This sensitivity highlights the importance of sourcing the material from suppliers who adhere to stringent quality control and packaging standards.

The applications of N-Acetoxysuccinimide are diverse and impactful. In peptide synthesis, it acts as an effective activating agent for carboxylic acids, forming activated esters that readily react with amines to create amide bonds. This process is essential for building peptide chains with high efficiency and minimal epimerization, a critical factor for therapeutic peptide development. Procurement managers and R&D scientists often seek out high-purity N-Acetoxysuccinimide to ensure the success of these sensitive reactions.

Beyond peptide synthesis, N-Acetoxysuccinimide is also a valuable tool in bioconjugation chemistry. It can be employed to modify biomolecules, such as proteins and antibodies, for a variety of research purposes, including labeling, immobilization, and the development of diagnostic assays. Its ability to form stable linkages makes it a preferred reagent for researchers aiming to create complex bioconjugates with specific functionalities.

Furthermore, as a fine chemical intermediate, N-Acetoxysuccinimide contributes to a wide array of organic synthesis pathways. It serves as a building block in the creation of novel compounds, participating in reactions that lead to the formation of various heterocyclic structures and functionalized organic molecules. The demand for reliable suppliers, especially those offering competitive pricing from regions like China, remains high for this essential chemical.

For businesses looking to buy N-Acetoxysuccinimide, partnering with a reputable manufacturer that guarantees high purity (≥98.0% HPLC) and provides excellent technical support is crucial. The chemical's moisture sensitivity means that sourcing from experienced suppliers who manage logistics and storage properly is key to ensuring product performance. Whether for research laboratories or large-scale manufacturing, N-Acetoxysuccinimide remains a vital component in the toolkit of modern chemists.