For professionals working with fine chemicals and pharmaceutical intermediates, a thorough understanding of a compound's properties is critical for safe and effective use. N-Acetyl-2-(4-Nitrophenyl)ethylamine (CAS 6270-07-1) is no exception. This compound, often supplied as a light yellow powder with a purity of ≥98.0%, plays a significant role in organic synthesis, particularly as an intermediate for pharmaceuticals like Dofetilide. Knowing its physical and chemical characteristics, along with proper handling procedures, is essential for anyone looking to buy or utilize this chemical.

Key Chemical and Physical Properties

N-Acetyl-2-(4-Nitrophenyl)ethylamine (C10H12N2O3) possesses several important properties that dictate its reactivity and application:

  • Appearance: Typically described as a light yellow powder.
  • Purity: Standard commercial offerings usually meet a purity of 98.0% or higher, often confirmed by GC analysis.
  • Melting Point: The melting point is a key indicator of purity and is generally reported around 140°C.
  • Molecular Weight: 208.21 g/mol.
  • Solubility: While not explicitly detailed in all sources, similar aromatic nitro compounds suggest moderate solubility in organic solvents and low solubility in water.
  • Reactivity: The presence of the nitro group (-NO2) makes the aromatic ring susceptible to reduction reactions, a common step in its use as an intermediate. The acetamide group (-NHCOCH3) can influence polarity and stability.

Safety and Storage Guidelines

As with all chemical compounds, safe handling of N-Acetyl-2-(4-Nitrophenyl)ethylamine is paramount. While specific hazard classifications can vary, general precautions for organic chemicals, especially those with nitro groups, should be followed:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including safety goggles, gloves, and a lab coat, when handling this substance.
  • Ventilation: Work in a well-ventilated area or under a fume hood to avoid inhalation of dust or vapors.
  • Storage: The recommended storage temperature is typically between 2-8°C. Store in a cool, dry, and well-ventilated place, away from incompatible materials such as strong oxidizing agents. Keep containers tightly closed.
  • Hazard Information: While detailed toxicity data might be limited in public sources, nitro-substituted aromatic compounds can sometimes be irritants or have other health effects. Consult the Safety Data Sheet (SDS) provided by the manufacturer for comprehensive hazard information.

Sourcing from Reliable Manufacturers

When you decide to buy N-Acetyl-2-(4-Nitrophenyl)ethylamine, selecting a reputable manufacturer or supplier is key to ensuring you receive a product that meets these specifications and comes with adequate safety information. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of such intermediates, committed to quality and safety. If you are seeking a reliable source for CAS 6270-07-1, we invite you to contact us to discuss your requirements and obtain a quotation. We ensure that our products are handled and supplied with the utmost care and professionalism.