For chemists, researchers, and procurement specialists in the pharmaceutical and fine chemical industries, a deep understanding of chemical intermediates is crucial. N-Acetyl-L-phenylalanine (CAS 2018-61-3) is one such compound, valued for its specific chemical characteristics that lend themselves to diverse synthetic applications. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier, details the key chemical properties of this important intermediate.

N-Acetyl-L-phenylalanine: Chemical Profile

N-Acetyl-L-phenylalanine is an acetylated derivative of the naturally occurring amino acid L-phenylalanine. Its structure combines a chiral alpha-carbon with a benzyl side chain, and an acetyl group attached to the amine nitrogen. This acetylation protects the amine group and modifies its reactivity, making it a useful intermediate in multi-step syntheses.

  • Chemical Name: N-Acetyl-L-phenylalanine
  • CAS Number: 2018-61-3
  • Molecular Formula: C11H13NO3
  • Molecular Weight: 207.23 g/mol
  • IUPAC Name: (2S)-2-acetamido-3-phenylpropanoic acid
  • Appearance: Typically described as a white to off-white fine crystalline powder or needles. This consistent appearance is a good indicator of product quality and manufacturing control.
  • Chirality: The compound possesses a chiral center at the alpha-carbon, with the L-configuration being the biologically relevant form. This stereochemical purity is vital for pharmaceutical applications where specific enantiomers are required.
  • Purity: High purity is essential. Reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. offer N-Acetyl-L-phenylalanine with a purity of ≥99%, often verified by HPLC.
  • Solubility: While specific solubility data can vary slightly, it is generally soluble in polar organic solvents such as ethanol, methanol, and dimethylformamide (DMF). Its solubility characteristics are important for selecting appropriate reaction media.
  • Melting Point: The melting point is typically in the range of 171-173°C (lit.), serving as another benchmark for purity and identity.

Significance in Synthesis and Research

The chemical properties of N-Acetyl-L-phenylalanine make it a valuable intermediate for:

  • Peptide synthesis as a protected amino acid derivative.
  • Chiral synthesis where its defined stereochemistry is critical.
  • Building block for complex organic molecules and Active Pharmaceutical Ingredients (APIs).
  • Biochemical studies related to amino acid metabolism and protein interactions.

Sourcing N-Acetyl-L-phenylalanine

For those looking to buy N-Acetyl-L-phenylalanine (CAS 2018-61-3), it is crucial to source from a reliable N-Acetyl-L-phenylalanine supplier that can guarantee these specifications. NINGBO INNO PHARMCHEM CO.,LTD. offers this intermediate with confirmed purity and comprehensive documentation. We encourage researchers and procurement professionals to contact us for detailed specifications, availability, and to request a quotation. Understanding the chemical profile ensures you select the right intermediate for your synthesis needs.