Understanding the fundamental chemical structure and properties of a compound is the first step for any chemist or researcher aiming to utilize it effectively. 2-Chloro-4,6-diphenylpyrimidine (CAS: 2915-16-4) is a molecule of significant interest in organic chemistry due to its versatile reactivity and potential applications. This article breaks down its core characteristics, making it easier for professionals to assess its suitability for their synthesis projects.

Decoding the Structure: 2-Chloro-4,6-diphenylpyrimidine

The name itself provides significant clues about the molecule's architecture. It is a pyrimidine derivative, meaning it contains a pyrimidine ring – a six-membered heterocyclic aromatic ring with two nitrogen atoms at positions 1 and 3. In 2-Chloro-4,6-diphenylpyrimidine:

  • A chlorine atom is attached to the carbon at position 2 of the pyrimidine ring.
  • Two phenyl groups (C6H5-) are attached to the carbons at positions 4 and 6 of the pyrimidine ring.

The molecular formula is C16H11ClN2, and its molecular weight is approximately 266.73 g/mol. The IUPAC name is 2-chloro-4,6-diphenylpyrimidine. The presence of conjugated phenyl rings contributes to its aromatic stability and influences its electronic properties.

Physical and Chemical Properties

The physical state of 2-Chloro-4,6-diphenylpyrimidine at room temperature is typically described as a white to light yellow solid, often in powder or crystalline form. Key reported physical properties include:

  • Melting Point: Generally reported in the range of 113.0 to 117.0 °C. This is a crucial parameter for assessing purity and for planning reactions that require specific temperature controls.
  • Boiling Point: Predicted boiling point is around 469.1 ± 14.0 °C.
  • Density: Approximately 1 ± 0.06 g/cm³.
  • Purity: Commercially available grades typically offer purities of 95% to over 98% (often determined by GC). For demanding applications like pharmaceutical synthesis, higher purity is preferred.
  • Solubility: It generally exhibits moderate solubility in common organic solvents. Specific solubility data would depend on the solvent and temperature.

Chemically, the most notable feature is the chlorine atom at the 2-position. This C-Cl bond is susceptible to nucleophilic substitution reactions, making 2-Chloro-4,6-diphenylpyrimidine a valuable electrophilic partner in coupling reactions and other synthetic transformations. This reactivity allows chemists to readily introduce or modify the pyrimidine core structure.

Procurement and Synthesis Considerations

For chemists looking to buy 2-Chloro-4,6-diphenylpyrimidine, understanding these properties is essential for successful procurement and experimental design. When you search for a ‘2-Chloro-4,6-diphenylpyrimidine manufacturer’, it’s wise to ensure they provide detailed specifications and a Certificate of Analysis. High-quality material from reliable suppliers, including those in China, is readily available. Whether you are a researcher in an academic lab or a formulator in an industrial setting, having access to well-characterized intermediates is crucial for efficient and predictable synthesis.

We are a trusted manufacturer and supplier, committed to providing researchers with high-purity 2-Chloro-4,6-diphenylpyrimidine. Feel free to reach out for detailed specifications, pricing, and to secure your supply.