Organic synthesis is the backbone of numerous industries, from pharmaceuticals and agrochemicals to advanced materials. At the heart of this discipline lie versatile chemical intermediates that enable the construction of complex molecules. One such compound gaining attention for its utility is 2-Chloro-4,6-diphenylpyrimidine (CAS: 2915-16-4). This article delves into its chemical properties, synthesis methods, and its significant role in modern organic synthesis, highlighting why researchers and formulators seek to buy this compound.

Chemical Profile of 2-Chloro-4,6-diphenylpyrimidine

2-Chloro-4,6-diphenylpyrimidine is classified as a heterocyclic compound, specifically a pyrimidine derivative. Its structure features a pyrimidine ring with two phenyl substituents at the 4 and 6 positions and a chlorine atom at the 2 position. This chlorine atom is particularly reactive, making the molecule an excellent electrophilic substrate for nucleophilic substitution reactions. Typically presented as a white to light yellow solid, its melting point generally falls between 113-117 °C. The molecular formula is C16H11ClN2, with a molecular weight of approximately 266.73 g/mol. These characteristics make it a convenient reagent for many laboratory-scale and industrial synthesis operations.

Synthesis Pathways and Commercial Availability

The synthesis of 2-Chloro-4,6-diphenylpyrimidine often involves the reaction of a suitable pyrimidine precursor with phenylating agents, followed by chlorination, or vice-versa. Common routes might utilize palladium-catalyzed cross-coupling reactions or direct chlorination techniques. For researchers and manufacturers, reliable commercial availability is key. Many chemical manufacturers, especially those specializing in pharmaceutical intermediates, offer this compound. When considering where to purchase, looking for a dedicated 2-Chloro-4,6-diphenylpyrimidine manufacturer that emphasizes quality and offers competitive pricing is advisable. Sourcing from a reputable supplier in China can ensure both cost-effectiveness and product integrity.

Applications in Organic Synthesis and Beyond

The reactivity of the chlorine atom in 2-Chloro-4,6-diphenylpyrimidine makes it a potent synthon for introducing the 4,6-diphenylpyrimidine moiety into various molecular frameworks. Its applications span several fields:

  • Pharmaceuticals: It serves as a vital intermediate in the synthesis of drug candidates, contributing to the development of novel therapeutic agents targeting various diseases. Its structure can be modified to impart specific biological activities.
  • Agrochemicals: The pyrimidine scaffold is common in many pesticides and herbicides. 2-Chloro-4,6-diphenylpyrimidine can be used as a starting material for creating new crop protection agents.
  • Materials Science: Its aromatic and heterocyclic nature suggests potential uses in the development of organic electronic materials, fluorescent probes, or specialized polymers, where tailored electronic and optical properties are desired.
  • Research and Development: It is a frequently used reagent in academic and industrial research laboratories for exploring new reaction methodologies and synthesizing complex organic molecules.

For scientists looking to innovate, procuring high-quality 2-Chloro-4,6-diphenylpyrimidine is a fundamental step. By partnering with a reliable chemical manufacturer, you can ensure the success of your synthetic endeavors. We are committed to being that partner, offering this crucial intermediate to fuel your next breakthrough.