As a leading supplier of fine chemical intermediates, understanding the manufacturing processes behind critical compounds like 1-Boc-3-Hydroxypyrrolidine (CAS: 103057-44-9) provides invaluable insight for our customers. This versatile intermediate, characterized by its C9H17NO3 formula and a molecular weight of 187.24 g/mol, is essential for numerous pharmaceutical and organic synthesis applications. At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on a rigorous approach to synthesis and quality control, ensuring that every batch of 1-Boc-3-Hydroxypyrrolidine meets the highest standards.

Manufacturing Process Overview

The synthesis of 1-Boc-3-Hydroxypyrrolidine typically involves the protection of the amine group of 3-hydroxypyrrolidine with a tert-butoxycarbonyl (Boc) group. This reaction is commonly carried out using di-tert-butyl dicarbonate (Boc anhydride) under controlled conditions, often in the presence of a base and a suitable solvent. The precise reaction parameters, such as temperature, reaction time, and reactant stoichiometry, are critical for achieving high yields and minimizing byproduct formation. Following the reaction, rigorous purification steps, which may include crystallization or chromatography, are employed to isolate the desired product. The final product is usually obtained as a white to off-white powder, with a melting point in the range of 62.1-62.2°C.

Quality Control: The Backbone of Our Production

For a compound like 1-Boc-3-Hydroxypyrrolidine, which is destined for sensitive pharmaceutical applications, stringent quality control is non-negotiable. Our manufacturing facilities are equipped with advanced analytical instrumentation to verify product purity and identity. Techniques such as High-Performance Liquid Chromatography (HPLC) are routinely used to confirm purity levels, typically ensuring they meet or exceed the 97% minimum specification. Gas Chromatography (GC), Nuclear Magnetic Resonance (NMR) spectroscopy, and Mass Spectrometry (MS) are also employed to characterize the compound and detect any trace impurities. Our commitment to quality means that when you buy 1-Boc-3-Hydroxypyrrolidine from us, you are assured of a product that performs reliably in your synthesis.

Why Partner with NINGBO INNO PHARMCHEM CO.,LTD.?

As a manufacturer based in China, we understand the global demand for cost-effective yet high-quality chemical intermediates. Our vertically integrated production processes and efficient supply chain management allow us to offer competitive pricing without compromising on product integrity. We offer flexible packaging options and adhere to strict storage guidelines (typically 2-8°C) to maintain product stability. For any research scientist or procurement manager looking to buy 1-Boc-3-Hydroxypyrrolidine, partnering with us means gaining access to a reliable source of this vital building block, backed by expert technical support.