The landscape of modern chemical synthesis is built upon a foundation of versatile intermediates, and 4-Fluorophenylacetic Acid (CAS 405-50-5) is a prime example of such a crucial compound. As a key building block, its unique structural features make it indispensable for a wide array of synthetic routes, particularly within the pharmaceutical and agrochemical sectors. For R&D scientists and product formulators, understanding its synthetic utility is key to unlocking new product development.

4-Fluorophenylacetic Acid: A Versatile Building Block

With its chemical formula C8H7FO2, 4-Fluorophenylacetic Acid offers chemists a phenylacetic acid scaffold functionalized with a fluorine atom. This fluorine substitution can significantly alter the electronic and lipophilic properties of the resulting molecules, influencing their biological activity, stability, and pharmacokinetic profiles. This makes it an attractive starting material for synthesizing complex organic compounds, including novel APIs (Active Pharmaceutical Ingredients) and performance chemicals.

Applications in Pharmaceutical Synthesis

The pharmaceutical industry heavily relies on intermediates like 4-Fluorophenylacetic Acid for the creation of life-saving and life-enhancing drugs. It serves as a precursor in the synthesis of fluorinated anesthetics, essential for surgical procedures. Beyond anesthetics, it's instrumental in developing compounds that target specific biological pathways. For instance, it's used in preparing antagonists for human A2B adenosine receptors, a focus in treating various inflammatory conditions, and in developing anti-HIV-1 agents. Scientists aiming to buy high-quality pharmaceutical intermediates will find 4-Fluorophenylacetic Acid a valuable component in their synthetic repertoire.

Beyond Pharmaceuticals: Agrochemicals and Specialty Chemicals

The utility of 4-Fluorophenylacetic Acid is not confined to human medicine. In agrochemistry, it acts as an intermediate in the synthesis of pesticides and herbicides, contributing to more effective crop protection and agricultural yields. Its reactivity also makes it suitable for producing various specialty chemicals used in materials science and other industrial applications. For businesses looking to innovate in these sectors, sourcing this intermediate from a reliable manufacturer is a strategic move.

Procuring 4-Fluorophenylacetic Acid: What Buyers Need to Know

When seeking to purchase 4-Fluorophenylacetic Acid, buyers should prioritize suppliers who can guarantee high purity (typically ≥98%) and consistency. Understanding the CAS number 405-50-5 is critical for accurate identification. Engaging with manufacturers, especially those based in China, can provide competitive pricing and a robust supply chain. It's advisable to request detailed product specifications, safety data sheets (SDS), and inquire about the manufacturer's production capabilities and quality assurance protocols. A strong supplier relationship ensures you can buy this intermediate reliably for your ongoing research and production needs.

In essence, 4-Fluorophenylacetic Acid is more than just an intermediate; it's a key enabler of innovation across multiple chemical-dependent industries. By understanding its role and sourcing it strategically, companies can accelerate their development of novel products and solutions.