When embarking on pharmaceutical development or advanced chemical synthesis, securing a reliable supply of high-purity intermediates is paramount. 4-Fluorophenylacetic Acid (CAS 405-50-5) stands out as a critical building block, particularly valued for its role in creating innovative drugs and specialty chemicals. For procurement managers and R&D scientists, understanding the nuances of this compound and where to source it effectively can significantly impact project timelines and success rates.

Understanding 4-Fluorophenylacetic Acid (CAS 405-50-5)

This aromatic carboxylic acid, characterized by a fluorine atom attached to the phenyl ring, is more than just a chemical compound; it's an enabler of scientific progress. Its molecular formula, C8H7FO2, and molecular weight of 154.14 are foundational, but its true value lies in its chemical reactivity and the properties it imparts to synthesized molecules. As a pharmaceutical intermediate, it plays a pivotal role in the synthesis of various therapeutic agents, including compounds that act as potent and selective human A2B adenosine receptor antagonists and agents targeting HIV-1.

Key Applications in the Pharmaceutical Industry

The versatility of 4-Fluorophenylacetic Acid is most evident in its pharmaceutical applications. It's a vital precursor in the synthesis of fluorinated anesthetics, which are indispensable for modern medical procedures, ensuring patient comfort and safety. Furthermore, its utility extends to the creation of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents where the fluorine atom can enhance pharmacological properties like bioavailability and metabolic stability. For any R&D scientist looking to buy advanced pharmaceutical intermediates, understanding the role of 4-Fluorophenylacetic Acid is key.

Sourcing Strategies for Procurement Managers

When you need to purchase 4-Fluorophenylacetic Acid, selecting the right manufacturer and supplier is crucial. Look for suppliers that can provide detailed Certificates of Analysis (CoA) confirming purity levels, typically 98% or higher. Transparency regarding production processes, quality control measures, and compliance with industry standards (like GMP where applicable) are indicators of a reliable partner. Consider suppliers who offer technical support and clear documentation, which are invaluable for R&D and process optimization.

Finding a Reliable 4-Fluorophenylacetic Acid Supplier in China

China has emerged as a global hub for fine chemical and pharmaceutical intermediate manufacturing. For procurement professionals seeking to buy 4-Fluorophenylacetic Acid, identifying a reputable manufacturer in China can offer cost efficiencies and broad access to supply. Companies that specialize in advanced organic synthesis and have a strong track record in exporting pharmaceutical intermediates are prime candidates. When inquiring about price, consider the total value proposition, which includes product quality, regulatory compliance, and reliable delivery schedules. Engaging with a trusted manufacturer ensures that your sourcing requirements for critical intermediates like 4-Fluorophenylacetic Acid are met with professionalism and expertise.

In conclusion, for companies aiming to innovate in pharmaceuticals and specialty chemicals, a consistent and high-quality supply of intermediates like 4-Fluorophenylacetic Acid is non-negotiable. By focusing on key specifications and partnering with established manufacturers, procurement managers can secure the essential materials needed to drive their projects forward.