The Chemistry of 1-(2,6-Dichlorophenyl)indolin-2-one: A Versatile Pharmaceutical Intermediate
In the intricate world of pharmaceutical chemistry, intermediates like 1-(2,6-Dichlorophenyl)indolin-2-one (CAS: 15362-40-0) are the unsung heroes. This compound, characterized by its unique chemical structure and properties, serves as a critical building block in the synthesis of various pharmaceuticals, most notably as a precursor or impurity related to Diclofenac.
The chemical identity of 1-(2,6-Dichlorophenyl)indolin-2-one is defined by its molecular formula C14H9Cl2NO and a molecular weight of 278.13 g/mol. Typically presenting as an off-white to light brown crystalline solid, its physical characteristics are important for handling and processing in industrial settings. The compound's stability under standard temperature and pressure conditions further enhances its utility as a reliable intermediate.
Researchers and manufacturers are drawn to 1-(2,6-Dichlorophenyl)indolin-2-one for its synthetic versatility. Its preparation can be achieved through several pathways, including intramolecular lactamization and various cyclization reactions. The ability to synthesize this compound efficiently, whether through traditional organic synthesis methods or more modern, sustainable approaches, is key to its widespread use.
Beyond its role in Diclofenac-related syntheses, studies have indicated that indole derivatives, including this compound, may possess a range of biological activities. This opens avenues for its exploration in medicinal chemistry for the development of novel therapeutic agents. The ongoing research into its properties and applications underscores its importance in advancing pharmaceutical innovation.
For procurement, companies that manufacture or supply such specialized chemicals, such as NINGBO INNO PHARMCHEM CO.,LTD., play a vital role in the pharmaceutical supply chain. Ensuring the quality and consistent availability of intermediates like 1-(2,6-Dichlorophenyl)indolin-2-one is fundamental to the success of drug development and manufacturing processes globally.
The chemical identity of 1-(2,6-Dichlorophenyl)indolin-2-one is defined by its molecular formula C14H9Cl2NO and a molecular weight of 278.13 g/mol. Typically presenting as an off-white to light brown crystalline solid, its physical characteristics are important for handling and processing in industrial settings. The compound's stability under standard temperature and pressure conditions further enhances its utility as a reliable intermediate.
Researchers and manufacturers are drawn to 1-(2,6-Dichlorophenyl)indolin-2-one for its synthetic versatility. Its preparation can be achieved through several pathways, including intramolecular lactamization and various cyclization reactions. The ability to synthesize this compound efficiently, whether through traditional organic synthesis methods or more modern, sustainable approaches, is key to its widespread use.
Beyond its role in Diclofenac-related syntheses, studies have indicated that indole derivatives, including this compound, may possess a range of biological activities. This opens avenues for its exploration in medicinal chemistry for the development of novel therapeutic agents. The ongoing research into its properties and applications underscores its importance in advancing pharmaceutical innovation.
For procurement, companies that manufacture or supply such specialized chemicals, such as NINGBO INNO PHARMCHEM CO.,LTD., play a vital role in the pharmaceutical supply chain. Ensuring the quality and consistent availability of intermediates like 1-(2,6-Dichlorophenyl)indolin-2-one is fundamental to the success of drug development and manufacturing processes globally.
Perspectives & Insights
Agile Reader One
“The ongoing research into its properties and applications underscores its importance in advancing pharmaceutical innovation.”
Logic Vision Labs
“For procurement, companies that manufacture or supply such specialized chemicals, such as NINGBO INNO PHARMCHEM CO.”
Molecule Origin 88
“Ensuring the quality and consistent availability of intermediates like 1-(2,6-Dichlorophenyl)indolin-2-one is fundamental to the success of drug development and manufacturing processes globally.”