The Chemistry of 2-Ethylphenylboronic Acid: Properties and Uses
Organoboron compounds, characterized by the presence of a carbon-boron bond, are indispensable tools in modern organic chemistry. Among these, boronic acids have garnered immense attention for their stability, reactivity, and broad applicability, particularly in carbon-carbon bond formation. 2-Ethylphenylboronic Acid (CAS 90002-36-1) is a prime example, offering a unique combination of a phenyl ring, an ethyl substituent, and a boronic acid functional group that make it highly valuable across various scientific disciplines.
Chemically, 2-Ethylphenylboronic Acid typically presents as a white powder with a molecular weight of approximately 149.98 g/mol. Its structure, C8H11BO2, features the boronic acid group [-B(OH)2] attached to the phenyl ring at the ortho position relative to the ethyl group. This specific arrangement influences its electronic properties and steric hindrance, which can be exploited to fine-tune reactivity in chemical transformations. The compound is generally soluble in polar organic solvents like ethanol and methanol, though its solubility in water is limited.
The most prominent application of 2-Ethylphenylboronic Acid is its role as a coupling partner in the Suzuki-Miyaura reaction. This palladium-catalyzed cross-coupling is celebrated for its efficiency, tolerance to various functional groups, and mild reaction conditions, making it ideal for synthesizing complex organic molecules. By reacting with aryl or vinyl halides, this boronic acid enables the creation of new carbon-carbon bonds, which is fundamental in constructing diverse molecular scaffolds. Researchers often buy this compound to introduce the 2-ethylphenyl moiety into target structures, contributing to the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
Beyond its utility in Suzuki couplings, 2-Ethylphenylboronic Acid is also explored for its potential in materials science. The boron atom's ability to interact with diols and other nucleophilic species opens avenues for developing novel sensors, polymers, and functional materials with tailored properties. When considering its price and availability, it is essential to partner with a reliable supplier that can guarantee the compound's purity and consistent supply, ensuring that your research and production efforts are well-supported.
For those in need of this chemical, understanding its basic chemistry and applications is the first step. Whether you are a research scientist exploring new synthetic pathways or a procurement manager sourcing critical raw materials, identifying a dependable manufacturer or supplier is key to ensuring project success.
Perspectives & Insights
Alpha Spark Labs
“Organoboron compounds, characterized by the presence of a carbon-boron bond, are indispensable tools in modern organic chemistry.”
Future Pioneer 88
“Among these, boronic acids have garnered immense attention for their stability, reactivity, and broad applicability, particularly in carbon-carbon bond formation.”
Core Explorer Pro
“2-Ethylphenylboronic Acid (CAS 90002-36-1) is a prime example, offering a unique combination of a phenyl ring, an ethyl substituent, and a boronic acid functional group that make it highly valuable across various scientific disciplines.”