The growing interest in cannabidiol (CBD) for its therapeutic properties has spurred significant advancements in its synthesis. For research and development scientists, understanding the chemical intermediates involved is crucial for optimizing production and exploring new applications. (1S,4R)-p-Menth-2,8-dien-1-ol, also known by its synonym cis-Isolimonenol and CAS number 22972-51-6, plays a pivotal role in this process. As a specialized chemical supplier, we provide critical information for R&D professionals looking to procure this vital compound.

The Significance of (1S,4R)-p-Menth-2,8-dien-1-ol in CBD Synthesis

(1S,4R)-p-Menth-2,8-dien-1-ol is a chiral terpene derivative that serves as a key precursor in many synthetic routes leading to CBD. Its specific molecular structure and stereochemistry are instrumental in achieving the correct formation of the cannabinoid backbone. The compound's purity, typically specified at 98.0% or higher, is paramount for efficient conversion and to minimize unwanted byproducts in the final CBD product. Its contribution to the synthesis of compounds exhibiting anti-spasm, anti-anxiety, anti-inflammatory, and analgesic effects makes it a subject of intense research within the pharmaceutical and nutraceutical industries.

Key Chemical Properties and Specifications for R&D

For scientists engaged in R&D, understanding the detailed specifications of (1S,4R)-p-Menth-2,8-dien-1-ol is essential. Its appearance as a white solid, molecular formula C10H16O, and molecular weight of 152.23 g/mol are fundamental data points. The compound's utility extends to its role as a building block in various organic syntheses, often requiring precise reaction conditions. When seeking to buy this intermediate, researchers should look for suppliers who provide comprehensive documentation, including Safety Data Sheets (SDS) and Technical Data Sheets (TDS), detailing handling procedures and chemical properties. Availability in standard packaging, such as 25kg bags or fiber drums, is also important for laboratory-scale work and pilot studies.

Sourcing Strategies for the Pharmaceutical Industry

Procurement managers in the pharmaceutical sector must ensure a reliable and high-quality supply of intermediates like (1S,4R)-p-Menth-2,8-dien-1-ol. Identifying manufacturers with robust quality control systems and proven expertise in fine chemical synthesis is crucial. Manufacturers based in China often offer competitive pricing and large-scale production capabilities, making them attractive partners. However, it is imperative to conduct thorough due diligence, verifying supplier credentials and product specifications through Certificates of Analysis (CoA). Establishing a dialogue with manufacturers to discuss pricing for bulk orders and potential sample provision is a standard and effective procurement strategy.

Future Trends and Research Opportunities

The ongoing research into cannabinoids and their derivatives continues to highlight the importance of intermediates such as (1S,4R)-p-Menth-2,8-dien-1-ol. As the demand for high-purity CBD grows, so too will the need for efficient and cost-effective synthesis routes, placing emphasis on the quality of precursor materials. Scientists may also explore novel applications for this intermediate in synthesizing other pharmacologically active molecules, expanding its utility beyond current applications. For those looking to purchase, partnering with experienced manufacturers ensures access to a consistent and quality-assured supply, supporting continuous innovation in the field.

In summary, (1S,4R)-p-Menth-2,8-dien-1-ol is a pivotal intermediate for CBD synthesis and broader R&D efforts. Understanding its chemical properties, synthesis, and sourcing options is key for scientists aiming to advance their research and development projects.