The pharmaceutical industry relies on a complex web of chemical intermediates to synthesize life-saving medications. Among these, Chloromethyl Carbonochloridate (CAS 22128-62-7) holds a significant position, primarily due to its indispensability in the production pathways of two vital drugs: Metronidazole and Tenofovir.

Chloromethyl Carbonochloridate, a colorless liquid with a purity often exceeding 98%, is a highly reactive organic compound. Its chemical structure makes it an ideal acylating agent and building block in organic synthesis. The specific reactivity patterns of Chloromethyl Carbonochloridate allow for precise chemical modifications that are essential for creating the active pharmaceutical ingredients (APIs) of Metronidazole and Tenofovir.

Metronidazole is a widely used antibiotic and antiprotozoal medication, critical for treating a range of infections, including those affecting the gastrointestinal tract, skin, and reproductive organs. The synthesis of Metronidazole often involves reactions where Chloromethyl Carbonochloridate plays a pivotal role, contributing the necessary functional groups to form the final API. Manufacturers looking for reliable sources to buy Chloromethyl Carbonochloridate for Metronidazole production prioritize high purity and consistent supply to meet global demand.

Similarly, Tenofovir is a cornerstone in the treatment and prevention of viral infections, most notably HIV/AIDS and Hepatitis B. As a nucleotide analog reverse transcriptase inhibitor, its synthesis is complex, and Chloromethyl Carbonochloridate serves as a key intermediate in certain synthetic routes. The demand for Tenofovir globally necessitates a stable and dependable supply chain for all its constituent intermediates, including Chloromethyl Carbonochloridate.

For pharmaceutical companies and contract manufacturing organizations (CMOs), sourcing this intermediate requires partnering with a reputable manufacturer. When searching for a supplier of Chloromethyl Carbonochloridate, particularly one based in regions like China, buyers should focus on factors like quality control, production capacity, and regulatory compliance. Ensuring that the supplier can provide the required documentation and meet stringent quality standards is paramount.

The price of Chloromethyl Carbonochloridate, especially when purchased in bulk for large-scale pharmaceutical production, is a significant consideration. Companies often compare quotes from various suppliers to secure the best possible pricing for CAS 22128-62-7. The ability of a manufacturer to offer both competitive pricing and unwavering quality makes them an invaluable partner in the pharmaceutical supply chain. In essence, the consistent availability of high-grade Chloromethyl Carbonochloridate directly impacts the accessibility of essential medications like Metronidazole and Tenofovir worldwide.