The pharmaceutical industry constantly seeks reliable sources for critical chemical intermediates that form the backbone of life-saving medications. Chloromethyl Isopropyl Carbonate (CAS 35180-01-9) stands out as a paramount example, playing an indispensable role in the synthesis of potent antiviral agents, most notably Tenofovir.

For R&D scientists, formulation chemists, and procurement managers, a thorough understanding of this compound's characteristics and its supply chain is crucial. This article provides an in-depth look at Chloromethyl Isopropyl Carbonate, highlighting its properties, its vital application in antiviral drug manufacturing, and how to effectively source it from reputable global manufacturers and suppliers.

Essential Chemical Attributes of Chloromethyl Isopropyl Carbonate

Chloromethyl Isopropyl Carbonate (CAS 35180-01-9) is a chemical compound defined by its molecular formula C5H9ClO3 and molecular weight of 152.58. It is typically supplied as a clear, colorless to slightly yellow liquid. Key specifications commonly sought by the industry include a high purity level, often exceeding 99.0% as determined by gas chromatography (GC). This high degree of purity is essential for ensuring the efficiency and success of downstream synthesis reactions, particularly in the pharmaceutical sector.

Other important properties include its density (around 1.14-1.15 g/cm³) and refractive index. Due to its chemical nature, it is noted as being moisture-sensitive, necessitating appropriate storage conditions, typically in a cool, dry, and well-ventilated area, often under an inert atmosphere to maintain its integrity and purity over time. Understanding these physical and chemical attributes is vital for effective handling and application.

The Critical Role in Antiviral Drug Production

The significance of Chloromethyl Isopropyl Carbonate is profoundly evident in its application as a key intermediate in the synthesis of Tenofovir. Tenofovir is a highly effective nucleoside reverse transcriptase inhibitor, widely prescribed for the treatment of HIV/AIDS and chronic Hepatitis B. The specific chemical structure of Chloromethyl Isopropyl Carbonate makes it an ideal precursor for constructing the complex molecular framework of Tenofovir, contributing directly to the efficacy of these antiviral therapies.

For pharmaceutical companies, ensuring a consistent and high-quality supply of this intermediate is paramount. This directly impacts production yields, product quality, and ultimately, the availability of essential medications. Researchers exploring new antiviral compounds may also utilize this intermediate for its reactive functional groups.

Strategic Sourcing: Finding Reliable Suppliers

The global supply of Chloromethyl Isopropyl Carbonate involves numerous manufacturers and distributors. Identifying a reliable supplier, particularly one that emphasizes quality and consistency, is critical for procurement professionals. We, as a leading manufacturer and supplier based in China, are dedicated to providing high-purity Chloromethyl Isopropyl Carbonate that meets the stringent requirements of the pharmaceutical industry. We offer competitive pricing and a commitment to dependable supply.

When seeking to buy this intermediate, it is advisable to seek out suppliers who provide comprehensive technical documentation, such as Certificates of Analysis (CoAs), and who can demonstrate robust quality control systems. Engaging with us means partnering with a supplier focused on delivering excellence and supporting your critical production needs. Feel free to reach out for a quote and to learn more about how we can be your trusted partner for Chloromethyl Isopropyl Carbonate.