The selection of an appropriate contrast agent is a critical decision in optimizing Magnetic Resonance Imaging (MRI) procedures. Gadobutrol (CAS: 138071-82-6) has emerged as a leading choice among MRI contrast agents due to its advanced properties and proven efficacy. NINGBO INNO PHARMCHEM CO.,LTD., a trusted manufacturer and supplier of pharmaceutical intermediates based in China, is dedicated to providing this high-quality product to meet the diverse needs of the medical imaging community.

Gadobutrol is a macrocyclic, extracellular, non-ionic gadolinium-based contrast agent (GBCA). Its distinguishing feature is its high concentration, typically formulated at 1.0 mmol/mL. This higher concentration compared to standard 0.5 mmol/mL agents offers significant advantages. Firstly, it allows for a reduced injection volume, which can streamline the imaging process and improve patient throughput. Secondly, the higher concentration results in a more compact and intense contrast bolus. This is particularly beneficial for dynamic MRI techniques such as Magnetic Resonance Angiography (MRA) and perfusion imaging, where the timing and sharpness of contrast enhancement are crucial for accurate interpretation. The enhanced relaxivity of Gadobutrol also plays a vital role, effectively shortening T1 relaxation times and thereby increasing signal intensity on T1-weighted images, which leads to superior contrast between different tissues and pathologies.

The broad applicability of Gadobutrol makes it a valuable asset in various diagnostic contexts. In Central Nervous System (CNS) imaging, it is essential for identifying abnormalities related to disrupted blood-brain barriers and altered vascularity, crucial for diagnosing tumors, inflammatory lesions, and cerebrovascular diseases. Its use in MRA significantly enhances the visualization of arteries, aiding in the detection of stenotic lesions, occlusions, and aneurysms in areas like the renal and supra-aortic arteries. Furthermore, Gadobutrol plays a key role in Cardiac MRI (CMRI) by improving the assessment of myocardial perfusion and the detection of myocardial scarring, providing critical data for the management of ischemic heart disease.

For healthcare providers and researchers, selecting a dependable supplier is paramount when procuring specialized chemical compounds. NINGBO INNO PHARMCHEM CO.,LTD. serves as a reliable supplier in China, committed to delivering consistent quality and adherence to international standards. We understand the importance of efficient procurement and offer competitive pricing for Gadobutrol, especially for bulk orders, making it an accessible choice for your clinical and research endeavors. As an experienced manufacturer, we ensure the integrity and purity of our products.

Choosing the right MRI contrast agent can significantly impact diagnostic outcomes. Gadobutrol, with its superior concentration, enhanced relaxivity, and macrocyclic stability, offers a compelling option for many imaging needs. We invite you to contact NINGBO INNO PHARMCHEM CO.,LTD. to request a quote and learn more about how our high-quality Gadobutrol can benefit your practice. Partner with us for reliable access to essential diagnostic agents.