In the complex world of pharmaceutical synthesis, specific chemical intermediates serve as the foundational building blocks for life-saving medications. Among these, 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine, with CAS number 877399-73-0, has emerged as a compound of significant importance. This off-white powder plays a pivotal role, particularly in the development and manufacturing of targeted cancer therapies. For researchers and procurement managers in the pharmaceutical sector, understanding the properties and sourcing of this intermediate is paramount.

The primary application that elevates the importance of 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine is its indispensable role as an intermediate in the synthesis of Crizotinib. Crizotinib is a groundbreaking drug used to treat specific types of non-small cell lung cancer (NSCLC), targeting patients with anaplastic lymphoma kinase (ALK) gene rearrangements. The intricate multi-step process to create Crizotinib relies heavily on the precise structure and high purity of its precursors. The presence of the iodine atom on the pyrazole ring within this intermediate facilitates crucial chemical reactions, making it a critical component in achieving the final active pharmaceutical ingredient (API).

When sourcing this vital compound, quality and reliability are non-negotiable. Manufacturers and suppliers who can consistently deliver 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine with an assay of ≥98.0% are highly sought after. This commitment to purity ensures that the downstream synthesis processes are efficient and that the final drug product meets stringent regulatory standards. For companies looking to buy 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine, partnering with a reputable pharmaceutical intermediate manufacturer, especially one based in China known for its advanced chemical production capabilities, is a strategic advantage. Such suppliers can offer competitive 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine price points without compromising on quality, making them an attractive option for both R&D and large-scale production needs.

The physical and chemical properties of 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine, such as its density and molecular weight (377.221 g/mol), are well-characterized, enabling efficient handling and reaction planning. Its low volatility and stable form as an off-white powder further contribute to its suitability in pharmaceutical manufacturing settings. For those in the market to purchase 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine, engaging with a trusted 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine supplier in China like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to consistent quality and supply chain stability. Exploring custom synthesis options for this or related compounds can also be a key strategy for advancing pharmaceutical research and development.