In the realm of organic chemistry and pharmaceutical synthesis, the precise structure and reliable supply of intermediates are foundational. 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine, identified by its CAS number 877399-73-0, is a prime example of such a critical building block. This compound, characterized by its off-white powder form and molecular formula C13H20IN3O2, plays a significant role, especially in the development of advanced pharmaceuticals like Crizotinib, a vital cancer therapeutic. Understanding its chemical significance is key for anyone looking to buy 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine.

The chemical architecture of 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine is meticulously designed for specific synthetic transformations. The presence of the protected piperidine ring and the iodinated pyrazole moiety makes it an ideal substrate for various coupling reactions, such as palladium-catalyzed Suzuki or Buchwald-Hartwig aminations. These reactions are fundamental in constructing complex molecular frameworks, essential for creating potent drug molecules. The high purity, typically ≥98.0%, ensures that these reactions proceed efficiently with minimal side products, a critical factor for pharmaceutical manufacturing. As a key intermediate for Crizotinib synthesis, its quality directly impacts the final drug’s efficacy.

For pharmaceutical companies and research institutions, sourcing this compound reliably is a strategic necessity. Identifying a reputable 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine manufacturer in China offers access to both advanced synthesis capabilities and competitive pricing. NINGBO INNO PHARMCHEM CO.,LTD., as a leading pharmaceutical intermediate supplier, provides this crucial compound, ensuring adherence to strict quality control measures. The ability to obtain competitive 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine price quotes and samples facilitates informed purchasing decisions, allowing researchers to evaluate its suitability for their specific synthesis pathways.

The chemical significance extends beyond its role in Crizotinib. Its structure offers versatility for exploring novel drug candidates and creating diverse chemical libraries. Whether for direct use in established synthesis routes or as a starting point for custom synthesis projects, having a dependable source is vital. Engaging with experienced chemical manufacturers ensures that the compound meets the required physical and chemical properties, including proper handling and storage guidelines (e.g., storing in a cool, ventilated place). For those looking to procure high-quality intermediates, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable partner, facilitating innovation in drug discovery.