Cyclopropanecarbonyl Chloride: A Versatile Building Block in Chemical Synthesis
The world of chemical synthesis is built upon a foundation of versatile building blocks, and Cyclopropanecarbonyl Chloride (CAS 4023-34-1) stands out as a prime example. This reactive intermediate, characterized by its unique cyclopropane ring fused with a carbonyl chloride moiety, offers chemists unparalleled opportunities to introduce specific structural features into target molecules. Its significance spans across multiple sectors, from the development of life-saving pharmaceuticals to the creation of advanced agrochemicals.
Understanding the chemical profile of Cyclopropanecarbonyl Chloride is the first step towards leveraging its full potential. With a molecular formula of C4H5ClO and a molecular weight of 104.53, it presents as a clear, colorless to slightly yellow liquid. Its boiling point is approximately 119°C, and it has a density of 1.152 g/mL at 25°C. Notably, it is moisture-sensitive and prone to decomposition in the presence of water, a characteristic common to many acid chlorides, requiring careful handling and storage protocols. The refractive index of n20/D is 1.452, providing another key physical property for identification and quality control.
The primary utility of Cyclopropanecarbonyl Chloride lies in its function as an acylating agent. The electrophilic nature of the carbonyl carbon, activated by the chlorine atom, makes it highly reactive towards nucleophiles such as alcohols, amines, and thiols. This reactivity enables the formation of esters, amides, and thioesters, respectively, which are fundamental linkages in many organic compounds.
In pharmaceutical synthesis, this compound is invaluable. It is frequently used to synthesize pharmacologically active molecules where the cyclopropane ring can enhance potency, improve metabolic stability, or alter receptor binding. The ability to reliably source high-purity Cyclopropanecarbonyl Chloride from manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for drug discovery and development pipelines. Researchers can buy this intermediate to explore new synthetic routes for potential drug candidates, often finding it to be a cost-effective solution compared to more complex or custom-synthesized reagents.
Similarly, in the agrochemical industry, Cyclopropanecarbonyl Chloride serves as a critical intermediate for manufacturing pesticides, herbicides, and fungicides. The incorporation of the cyclopropane ring can lead to compounds with enhanced biological activity and improved environmental profiles. Formulators seeking to develop more effective and sustainable crop protection agents often integrate this building block into their molecular designs.
For any scientist or procurement manager looking to buy Cyclopropanecarbonyl Chloride, partnering with a reputable manufacturer is key. Factors like consistent quality, reliable supply, competitive pricing, and responsive customer service are paramount. Companies that offer detailed product specifications and technical support ensure that users can effectively and safely utilize this versatile chemical. Explore the potential of this vital intermediate and enhance your chemical synthesis endeavors by connecting with our expert team.
In summary, Cyclopropanecarbonyl Chloride is more than just a chemical reagent; it is a gateway to innovation in molecular design, enabling the creation of advanced materials and compounds that drive progress across various scientific and industrial fields.
Perspectives & Insights
Data Seeker X
“The electrophilic nature of the carbonyl carbon, activated by the chlorine atom, makes it highly reactive towards nucleophiles such as alcohols, amines, and thiols.”
Chem Reader AI
“This reactivity enables the formation of esters, amides, and thioesters, respectively, which are fundamental linkages in many organic compounds.”
Agile Vision 2025
“It is frequently used to synthesize pharmacologically active molecules where the cyclopropane ring can enhance potency, improve metabolic stability, or alter receptor binding.”