D-Phenylglycinamide, identified by its CAS number 6485-67-2, is a compound of significant interest within the pharmaceutical industry. As a chiral intermediate, its precise molecular structure and high purity are essential for its application in the synthesis of complex Active Pharmaceutical Ingredients (APIs). This article delves into the key properties of D-Phenylglycinamide and its crucial role in drug development, emphasizing why sourcing from a dependable manufacturer is critical for researchers and procurement specialists.

The chemical identity of D-Phenylglycinamide is (2R)-2-amino-2-phenylacetamide. Its molecular formula, C8H10N2O, and molecular weight of approximately 150.18 g/mol, define its basic chemical characteristics. As a white to light yellow crystalline powder, it possesses a defined melting point range, typically between 125-129°C, which is a key parameter for quality control. The optical activity, often specified as α20D -125±5, c = 0.55 in ethanol, further confirms its specific stereochemistry – a critical aspect for its use in chiral synthesis.

One of the primary applications highlighted for D-Phenylglycinamide is its use as a raw material intermediate in the synthesis of Boceprevir. Boceprevir is a protease inhibitor used in the treatment of Hepatitis C. The specific chiral nature of D-Phenylglycinamide is integral to building the complex molecular architecture required for the efficacy of such drugs. For scientists working on new drug candidates or optimizing existing synthesis routes, having access to this compound from a reliable supplier is paramount. Understanding the price of D-Phenylglycinamide from various manufacturers allows for informed purchasing decisions, balancing budget constraints with the need for consistent quality.

When considering the procurement of D-Phenylglycinamide, especially in bulk quantities for industrial synthesis, it is important to look beyond just the product name and CAS number. Enquiries should also focus on the supplier's ability to provide consistent quality, robust documentation (including COAs), and timely delivery. For procurement managers, identifying a trustworthy manufacturer in China or other reputable regions can streamline the supply chain. The availability of D-Phenylglycinamide for research purposes, as well as for commercial scale synthesis, underscores its importance in the pharmaceutical R&D landscape.

In conclusion, D-Phenylglycinamide (CAS 6485-67-2) is more than just a chemical; it is a vital component in the creation of life-saving medicines. Its precise chemical specifications and role as a chiral building block necessitate careful sourcing. By prioritizing purity, reliable supply, and competitive pricing from established chemical suppliers, pharmaceutical companies can ensure the success of their drug development and manufacturing processes.