The efficient synthesis of complex organic molecules is often dependent on the availability of well-characterized and reactive chemical intermediates. 4-Bromo-2-pentene, identified by the CAS registry number 1809-26-3, is one such compound that plays a vital role in various chemical transformations. This article delves into its chemical behavior, common synthesis routes, and its broad utility across different sectors.

Physicochemical Profile of 4-Bromo-2-pentene

4-Bromo-2-pentene (C5H9Br) is an organobromine compound with a molecular weight of 149.03 g/mol. Its typical appearance is a white powder, although it is a liquid at ambient temperatures with a boiling point around 114.3°C. A critical aspect of this compound is its high purity, usually ≥99%, which is crucial for reliable outcomes in synthetic chemistry. The molecule contains a reactive bromine atom and a double bond, the interplay of which dictates its chemical reactivity and synthetic potential.

Synthesis Strategies and Reaction Mechanisms

The preparation of 4-Bromo-2-pentene is typically achieved through established organic synthesis methods. Common approaches include the hydrobromination of unsaturated hydrocarbons like 2-pentene or related isomers. The selection of specific reagents and reaction conditions is paramount to control selectivity and minimize unwanted byproducts. For instance, allylic bromination techniques can also be employed. The reactivity of 4-Bromo-2-pentene is notable. The bromine atom is susceptible to nucleophilic substitution reactions, where it can be replaced by a variety of nucleophiles, forming new carbon-heteroatom bonds. The presence of the double bond allows for addition reactions, such as halogenation or hydrohalogenation. Understanding these reaction mechanisms is key for chemists to effectively utilize this intermediate. Many chemical suppliers offer 4-bromo-2-pentene, allowing researchers to source it for their projects.

Industrial Significance and Applications

The principal application of 4-Bromo-2-pentene is as an intermediate in the pharmaceutical industry, where it is employed in the synthesis of Active Pharmaceutical Ingredients (APIs). Its structural features are leveraged to build complex molecular architectures essential for drug efficacy. Beyond pharmaceuticals, it serves as a versatile building block in the broader fine chemical sector, contributing to the development of specialized materials and research chemicals. The price of 4-bromo-2-pentene is a factor for procurement, and its availability from reliable suppliers ensures continuity in production and research timelines.

Reliable Sourcing and Quality Control

For chemists and manufacturers, sourcing high-quality 4-bromo-2-pentene is a critical step. Chemical suppliers provide detailed product specifications, including CAS number (1809-26-3), purity levels, and safety data. This ensures that the material is suitable for its intended applications. The competitive market for chemical intermediates means that consistent quality and reasonable pricing are key considerations for end-users.

In essence, 4-Bromo-2-pentene (CAS 1809-26-3) is a fundamental intermediate whose chemical properties and reactivity make it an indispensable tool for modern synthetic chemistry.