The pharmaceutical industry relies heavily on a robust supply of high-quality chemical intermediates to synthesize life-saving drugs. Among these crucial building blocks is 4-Bromo-2-pentene, identified by CAS number 1809-26-3. This versatile compound plays a pivotal role in numerous organic synthesis pathways, making it indispensable for the development of Active Pharmaceutical Ingredients (APIs).

Chemical Profile and Properties

4-Bromo-2-pentene, with the molecular formula C5H9Br and a molecular weight of approximately 149.03 g/mol, is typically presented as a white powder. Its chemical structure features a bromine atom and a double bond, contributing to its specific reactivity. Key properties include a high purity of ≥99%, which is essential for demanding pharmaceutical applications. While specific melting and boiling points can vary, estimated values suggest a low melting point and a boiling point around 114.3°C, indicating it is a liquid at standard laboratory temperatures, though often handled as a solid precursor in its pure form. Understanding the precise chemical properties of 4-bromo-2-pentene is critical for chemists aiming to optimize synthesis yields and ensure product purity.

Synthesis and Reactivity

The synthesis of 4-bromo-2-pentene often involves reactions such as the hydrobromination of pentadienes or other controlled bromination techniques. The presence of the allylic bromine atom makes it susceptible to nucleophilic substitution and elimination reactions. This reactivity is precisely what makes it a valuable intermediate. Chemists can leverage these reactions to introduce various functional groups or to extend carbon chains, building more complex molecular structures required for drug synthesis. The ability to buy 4-bromo-2-pentene from reliable suppliers ensures consistent quality for research and manufacturing.

Applications in Pharmaceutical Development

The primary application of 4-Bromo-2-pentene lies in its function as a pharmaceutical intermediate. It serves as a key starting material or building block in the multi-step synthesis of various APIs. Its structure allows for the precise introduction of chemical moieties that are critical for a drug's biological activity and therapeutic effect. For example, derivatives synthesized from 4-bromo-2-pentene might be incorporated into molecules designed to target specific enzymes or receptors within the human body. The cost-effectiveness and availability of 4-bromo-2-pentene as a chemical intermediate directly impact the affordability and accessibility of finished pharmaceutical products.

Sourcing and Availability

For research institutions and pharmaceutical companies, securing a consistent supply of high-purity 4-bromo-2-pentene is paramount. Suppliers specializing in fine chemicals and pharmaceutical intermediates offer this compound, often with detailed specifications regarding purity, CAS number, and handling instructions. The price of 4-bromo-2-pentene can fluctuate based on market demand, production costs, and purity levels, making it important for procurement specialists to stay informed about market trends. By partnering with reputable 4-bromo-2-pentene suppliers, companies can ensure the integrity and efficiency of their production processes.

In conclusion, 4-Bromo-2-pentene (CAS 1809-26-3) is more than just a chemical compound; it is a cornerstone in the intricate architecture of modern pharmaceuticals. Its unique properties and reactivity empower chemists to synthesize novel therapies, underscoring its vital role in advancing global health.