Direct compression (DC) is often the preferred method for tablet manufacturing due to its simplicity and cost-effectiveness, as it bypasses the granulation step. At NINGBO INNO PHARMCHEM CO.,LTD., we leverage excipients that are well-suited for this process, and Sodium Starch Glycolate (SSG) is a standout choice. As a highly effective superdisintegrant, SSG's properties make it an excellent candidate for direct compression formulations, ensuring both efficient tablet production and optimal disintegration performance.

Sodium Starch Glycolate (CAS No. 9063-38-1) is renowned for its ability to rapidly absorb water and swell, a mechanism that drives rapid tablet disintegration. For direct compression, the choice of excipients is critical, as they must possess good flowability and compressibility to form robust tablets without granulation. SSG meets these requirements, contributing to the formation of tablets that are hard enough to withstand handling while still disintegrating quickly upon exposure to moisture. Its ability to enhance disintegration at typical concentrations (2-10%) makes it a valuable asset in DC formulations, where uniform distribution of the disintegrant is key.

The advantage of using SSG in direct compression lies in its dual functionality: it acts as a disintegrant while also supporting tablet integrity. Unlike some disintegrants that can negatively impact tablet hardness when used in DC, SSG has been shown to improve it. This means that NINGBO INNO PHARMCHEM CO.,LTD. can produce high-quality tablets efficiently, without the need for complex granulation processes that add time and cost. The rapid water uptake of SSG ensures that even in a directly compressed matrix, the disintegration process is prompt and effective.

Our expertise at NINGBO INNO PHARMCHEM CO.,LTD. in formulating with Sodium Starch Glycolate for direct compression allows us to offer streamlined manufacturing processes and high-quality pharmaceutical products. By incorporating this versatile superdisintegrant, we ensure that our directly compressed tablets not only meet production efficiency goals but also deliver the expected therapeutic performance through rapid and reliable disintegration and API release. This makes SSG a cornerstone excipient for our direct compression tablet development.