In the pharmaceutical manufacturing sector, the procurement of raw materials and intermediates is a delicate balance of quality, cost, and availability. For intermediates like (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone (CAS 141645-16-1), used in the synthesis of Dronedarone, these three factors—price, purity, and supply—are especially critical. Understanding these elements is key for R&D scientists and procurement managers aiming to secure a stable and cost-effective supply chain.

Purity: The Foundation of Quality
The most fundamental requirement for any pharmaceutical intermediate is its purity. For (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone, a minimum purity of ≥99% is typically expected. This high level of purity ensures that subsequent chemical reactions proceed efficiently and that the final API, Dronedarone, meets stringent regulatory standards. Manufacturers must provide detailed Certificates of Analysis (CoA) to verify purity and list any impurities, usually with a strict limit such as ≤0.2%. Low moisture content (≤0.5%) is also vital for stability and reactivity.

Price: Strategic Procurement
While quality is paramount, price remains a significant consideration for procurement professionals. Manufacturers in China often offer competitive pricing for chemical intermediates due to economies of scale and efficient production processes. When seeking to buy (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone, it is advisable to request quotes from multiple reputable suppliers. This helps in assessing the market price and identifying suppliers who offer the best balance of cost and quality. Factors such as order volume and packaging requirements can also influence the final price.

Supply: Ensuring Continuity
A consistent and reliable supply chain is indispensable for pharmaceutical production. Any disruption in the availability of key intermediates can lead to significant delays and financial losses. Therefore, it is crucial to partner with manufacturers who have proven production capabilities and robust supply chain management. Companies looking to purchase this Dronedarone intermediate should inquire about a supplier's production capacity, lead times, and their ability to handle both small R&D orders and large commercial quantities. A dependable supplier will offer clear communication regarding inventory levels and delivery schedules, ensuring that production lines remain operational.

By carefully evaluating price, purity, and supply, pharmaceutical companies can make informed decisions when sourcing (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone, ensuring the seamless production of vital medications.