The pharmaceutical industry continuously seeks advanced solutions to combat bacterial infections. A key enabler in this endeavor is the availability of high-purity chemical intermediates that form the backbone of potent therapeutic agents. Among these, 3,4,5-Trimethoxybenzaldehyde (TMBA), with CAS number 86-81-7, stands out for its crucial role in synthesizing Trimethoprim. Trimethoprim is a widely recognized antibacterial drug, often used in combination therapies to amplify its efficacy and broaden its spectrum of activity.

Understanding the Chemical Profile of TMBA

TMBA, or 3,4,5-Trimethoxybenzaldehyde, is a fine chemical intermediate with precise specifications critical for its pharmaceutical applications. Its chemical formula is C10H12O4, and it has a molecular weight of 196.200. Typically supplied at a purity of 99% minimum, it appears as white to yellowish needle crystals. For buyers seeking to purchase 3,4,5-trimethoxybenzaldehyde, these attributes are vital indicators of quality. Its boiling point of 311.4±37.0 °C at 760 mmHg and a melting point of 72-74 °C further define its handling and processing parameters.

TMBA: A Cornerstone for Antibacterial Formulations

The significance of TMBA lies in its direct application in the synthesis of Trimethoprim. Trimethoprim acts as a potent inhibitor of bacterial dihydrofolate reductase, an enzyme essential for the synthesis of nucleic acids and proteins. By interfering with this metabolic pathway, Trimethoprim effectively halts bacterial growth. Its synergistic effect, particularly when combined with sulfonamides like sulfamethoxazole, makes it a cornerstone in treating urinary tract infections, respiratory infections, and other bacterial ailments. Therefore, ensuring a steady supply of high-quality TMBA is directly linked to the availability of these life-saving medications. Companies looking to source this intermediate often search for “CAS 86-81-7 price” to evaluate suppliers.

Partnering with Chinese Manufacturers for TMBA Supply

China has emerged as a global hub for chemical manufacturing, offering competitive pricing and a vast production capacity. For pharmaceutical companies, identifying a reliable 3,4,5-trimethoxybenzaldehyde manufacturer in China is a strategic decision. NINGBO INNO PHARMCHEM CO.,LTD. positions itself as a leading supplier, dedicated to providing pharmaceutical-grade intermediates. “We focus on rigorous quality control to ensure every batch of our 3,4,5-Trimethoxybenzaldehyde meets the exacting standards of the pharmaceutical industry,” states their team. They emphasize their commitment to being a dependable 3,4,5-trimethoxybenzaldehyde supplier, capable of handling both sample requests and bulk orders.

Conclusion

The role of 3,4,5-Trimethoxybenzaldehyde (CAS 86-81-7) in enhancing antibacterial efficacy through Trimethoprim synthesis cannot be overstated. For pharmaceutical developers and manufacturers, sourcing this critical intermediate from reputable China-based suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is key to ensuring product quality, cost-effectiveness, and supply chain resilience. Engaging with these manufacturers for quotes and samples is a critical step in solidifying your production capabilities for essential antibacterial treatments.